深圳市耐多药肺结核67例临床特点研究  

Clinical analysis of 67 multi-drug resistant tuberculosis cases in Shenzhen

作　　者：吕建文[1] 杨应周[1] 吕德良[1] 吴清芳[1] 张玉华[1] 管红云[1] 车晓玲[1] 李明珍[1] 

机构地区：[1]深圳市慢性病防治中心,广东深圳518020

出　　处：《中国热带医学》2011年第6期686-687,共2页China Tropical Medicine

基　　金：国家"十一五"重大科技专项"宝安区防治结核病规模化现场流行病学和干预的研究"(编号:2009ZX10003-018)

摘　　要：目的探讨深圳市耐多药肺结核的临床特点。方法回顾性分析2009～2010年在深圳市慢性病防治中心诊治的67例耐多药肺结核的临床资料。结果深圳市67例耐多药肺结核患者男、女之比为1.5:1,平均年龄为33.2岁,外来流动人口占深圳市耐多药肺结核的比例达92.5%。病变范围达4个及以上肺野占61.2%,伴病灶空洞形成占71.6%,耐4～5种抗结核药者占49.3%,伴合并症者占63%,其中以肝功异常比例最高,占22.4%。结论应高度重视流动人口对大城市耐多药肺结核防治的影响,建议高耐药地区初治结核病患者治疗前常规进行痰培养和药敏试验,以早期发现、早期合理治疗耐药结核病。Aim To analyze the clinical features of multi-drug resistant tuberculosis in Shenzhen City. Methods The clinical data of 67 MDR-TB cases in Shenzhen during 2009-2010 was retrospectively analyzed. Results The male and female ratio of 67 MDR-TB cases in Shenzhen was 1.5：1 ,the average age 33.2 years old,92.5% od the MDR-TB cases were among floating population. Lesions up to 4 and above of the lung field accounted for 61.2% ,with cavitation lesions accounted for 71.6%, 49.3% of the cases were resistant to 4 or 5 anti-TB drug,with complications accounted for 63% and 22.4% of them with abnormal liver function. Conclusions The work of MDR-TB control among floating population be strenthened and early detection and rational treatment are indicated with emphasis on the suputum culture and srug susceptibility tests.

关 键 词：结核 肺 耐多药 临床分析 

分 类 号：R521[医药卫生—内科学]