吉林市鲍曼不动杆菌药敏监测分析  

Nosocomial infection of Acinetobacter baumannii and its resistant to antibiotics

作　　者：李春辉[1] 孙可歆[2] 

机构地区：[1]北华大学附属医院同位素科,吉林吉林132011 [2]吉林医药学院检验系,吉林吉林132011

出　　处：《中国热带医学》2011年第6期709-710,共2页China Tropical Medicine

摘　　要：目的了解吉林市某大学医院鲍曼不动杆菌感染的临床分布及对常用抗菌药物的耐药状况。方法采用Vitek-32全自动细菌分析系统,对吉林市某大学医院2007年7月～2010年6月临床病人各类感染标本中分离出的375株鲍曼不动杆菌进行鉴定;药物敏感性试验采用纸片扩散(K-B)法,按当年度CLSI的标准对结果进行判读,分别对12种抗生素进行药物敏感试验。结果吉林市某大学医院2007年7月～2010年6月间医院内感染的鲍曼不动杆菌有明显逐年增多的趋势;最常出现在痰标本中,其次是脓液;鲍曼不动杆菌感染以院内为主,对抗生素耐药现象严重,而对亚胺培南耐药率最低。结论吉林市某大学医院院内感染分离的375株鲍曼不动杆菌以痰标本最常见,其次是脓液治疗建设使用耐药率最低的抗生素是亚胺培南。Aim To investigate the clinical distribution and drug resistance of Acinetobacter baumannii to the routine antibiotics from 2007 to 2010 in the affiliated hospital of Beihua University in Jilin Province. Methods Acinetobacter baumannii were identified by Vitek-32 automatic bacterial identification system. Drug resistance test was then performed by K-B method. Results A total of 375 Acinetobacter baumannii strains were isolated from various clinical specimens from July 2000 to June 2010. The nosocomial infection due to Acinetobacter bauraannii showed a rising trend. They happened most commonly in the sputum specimen ,the second was in pus. Most specimens were in the department of respiration, followed by the department of burn and plastic surgery and ICU. Most isolates were resistant to all antimicobial agents tested except imipenem. Conclusions A total of 375 Acinetobacter baumannii strains were isolated from sputum and pus specimens. They have the high isolation rate from the the departments of respiration,burn,plastic surgery and ICU, respectively. Acinetobacter baumannii was only sensitive to imipenem. Thus the surveillance of drug resistance of Acinetobacter baurnannii should be strengthened.

关 键 词：鲍曼不动杆菌 医院感染 抗菌药物 耐药性 

分 类 号：R372[医药卫生—病原生物学]