川芎嗪加普鲁卡因治疗儿童混合型过敏性紫癜效果观察  

Effect of ligustrazine in combination with procaine on infant henoch-Schonlein purpura patients

作　　者：李立佳 符梅竹[1] 阎青青[1] 黄月梅[1] 

机构地区：[1]海南医学院附属医院儿科,海南海口570102

出　　处：《中国热带医学》2011年第6期749-750,共2页China Tropical Medicine

摘　　要：目的观察川芎嗪加普鲁卡因治疗混合型过敏性紫癜疗效。方法对60例过敏性紫癜患儿随机分为治疗组与对照组各30例,对照组予常规治疗,疗程14～21d,治疗组予常规治疗基础上加川芎嗪和普鲁卡因静点治疗,疗程5～10d,比较两组症状缓解时间,住院天数及复发率。结果治疗组疗效明显优于对照组,治疗组皮肤紫癜消退(5.1±1.3)d,对照组为(10.2±2.4)d,治疗组平均症状缓解时间为4～6d,对照组为9～12d,治疗组与对照组住院天数分别为7～10d和13～16d,两组比较差异有统计学意义(P<0.01)。结论常规治疗基础上加用川芎嗪联合普鲁卡因治疗混合型过敏性紫癜疗效显著。Aim To observe the effect of ligustrazine combined with procaine on infant Henoch-Schonlein purpura patients. Methods Sixty Henoch-Schonlein purpura were randomly divided into treatment group and control group each consisted of 30 patients. Patients in the control group received conventional therapy and that in the treatment group received conventional therapy plus intravenous TMP and procaine treatment. The results of treatment in the two groups were compared. Results The disappearance time of skin purpura in the treatment group was 5.1±1.3 days and that in the control group was10.2±2.4 days; the average symptom relief time in the treatment and control groups were 4-6 days and 9-12 days; the hospitalization days in the treatment group and control group were 7-10 days and 13-16 days,all showing significant diffecereces （P〈0.01）. Conclusion Conventional therapy plus procaine and ligustrazine is effective for treatment of Henoch-Schonlein purpura pateints.

关 键 词：过敏性紫癜 混合型 川芎嗪 普鲁卡因 疗效 

分 类 号：R593.1[医药卫生—内科学]