血管内皮生长因子家族及其与肺纤维化关系  

Relationship of vascular endothelial growth factor family with lung fibrosis

作　　者：何秋颖[1] 谢敏[1] 

机构地区：[1]四川大学华西医院呼吸内科,成都610041

出　　处：《国际呼吸杂志》2011年第12期936-940,共5页International Journal of Respiration

摘　　要：血管内皮生长因子家族是近年发现的与血管内皮功能密切相关的一组生物活性物质。在内皮细胞的增殖、迁移、存活和血管通透性的维持，以及肿瘤生长转移、创伤组织修复、组织纤维化等多种生理和病理过程中发挥重要作用。文中将具与肺纤维化的关系作一综述。Vascular endothelial growth factor family is a group of bioactive substances discovered in recent years,which is closely related to function of vascular endothelium. It plays an important role in the proliferation, migration, and survival of endothelial cells,maintenance of vascular permeability, growth and metastasis of tumor, repair of wound tissue, fibrosis, and other physiological and pathological processes. This paper reviews the relationship of vascular endothelial growth factor family with pulmonary fibrosis.

关 键 词：血管内皮生长因子 肺纤维化 低氧 

分 类 号：R563.9[医药卫生—呼吸系统]