速度向量成像技术评估高血压病患者左室扭转运动的价值  

Evaluation of left ventricular twist by velocity vector imaging in patients with primary hypertension

作　　者：杨丽玲[1] 姜志荣[1] 郑娟[1] 

机构地区：[1]青岛大学医学院附属医院特检科,山东青岛266061

出　　处：《心脏杂志》2011年第3期364-367,共4页Chinese Heart Journal

摘　　要：目的:探讨速度向量成像(velocity vector imaging,VVI)技术评价高血压病患者左室扭转运动的临床价值。方法:应用彩色多普勒超声对28例正常人和68例原发性高血压患者,于胸骨旁左室心底部、心尖部经胸采集并存贮左室短轴二维图像,根据Ganau分类法,将原发性高血压患者分为3组:左室正常构型组(20例)、向心性肥厚型组(23例)和离心性肥厚型组(25例)。应用VVI脱机分析软件测量行脱机分析,计算并记录心底部旋转角度峰值(PBr),心尖部旋转角度峰值(PAr),左室扭转角度峰值(Ptw),解旋速度峰值(PutwV),解旋速度达峰时间(TPKutw)、等容舒张期解旋百分比(Iutw%)。结果:①与对照组相比,高血压病组左室PutwV增大,TPKutw延迟,Iutw%下降(P<0.05),高血压病各组间PutwV、TPKutw、Iutw%差异无统计学意义;正常构型组、向心性肥厚型组的Ptw明显增大(P<0.05,P<0.01),离心性肥厚型组Ptw下降(P<0.01),高血压病各组间Ptw差异有统计学意义(P<0.05,P<0.01)。②Ptw与左室射血分数(LVEF)呈正相关(r=0.65,P<0.05)。结论:VVI技术可以准确测量心室扭转角度,能从心肌解剖力学角度早期敏感评估高血压病患者的心功能变化。AIM： To probe into the clinical value of velocity vector imaging （VVI） in measuring left ventricular twist （LVtw） in patients with primary hypertension. METHODS： Systolic and diastolic heart wall motion on a basal and on an apical level of the myocardium were examined in 68 patients with primary hypertension and 28 age-matched healthy controls using color Dopple echocardiography. Based on Ganau, patients with primary hypertension were divided into three groups： normal geometry （20 cases） , concentric hypertrophy （23 cases） and eccentric hypertrophy （25 cases）. LVtw and uutwist were defined as apical rotation （rotation rate） relative to the basal level. RESULTS： Compared with controls, peak LV untwist velocity in patients with hypertension increased, the time to peak untwist velocity was prolonged, and the % isovolumic untwist decreased （P 〈 0. 05）. Peak LVtw was significantly higher in patients with concentric hypertrophy and normal geometry compared with controls （P 〈0. 05, P 〈0. 01 ）. Peak LVtw was significantly shorter in patients with eccentric hypertrophy compared with controls （P 〈0. 01 ）. Significant correlation was found between LVtw and LVEF （r = 0.65, P 〈 0.05 ）. CONCLUSION ： VVI is a reliable and noninvasive approach to measuring left ventricular torsional deformation and to evaluate early changes of heart function.

关 键 词：速度向量成像技术 扭转 高血压 原发性 

分 类 号：R541.1[医药卫生—心血管疾病]