新疆维吾尔族、哈萨克族、汉族成人颈动脉内中膜厚度与吸烟相关性研究  

Association between smoking and carotid intima-media thickness in Han,Uygur and Hazakh adults in Xinjing

作　　者：李维琼[1] 杨毅宁[1] 马依彤[1] 李晓梅[1] 袁山[1] 谢翔[1] 刘芬[1] 

机构地区：[1]新疆医科大学第一附属医院心脏中心冠心病科,乌鲁木齐市830054

出　　处：《中华实用诊断与治疗杂志》2011年第6期562-564,567,共4页Journal of Chinese Practical Diagnosis and Therapy

基　　金：新疆维吾尔自治区重大科技专项课题(200733146-3)

摘　　要：目的:探讨新疆地区汉族、维吾尔族(维族)、哈萨克族(哈族)3个民族成人颈动脉内中膜厚度(intima-mediathicknes,IMT)的差别及与吸烟的相关性。方法:应用四阶段整群随机抽样法调查6个地区年龄≥35岁汉、维、哈3个民族的样本,男女均衡。比较不同吸烟人群、不同民族、年龄段、性别的颈动脉IMT,采用多元逐步回归分析IMT的影响因素。结果:由协方差分析调整了年龄、性别、体质量指数等因素后,3个民族中吸烟组及戒烟组颈动脉IMT高于不吸烟组(P<0.05),戒烟组颈动脉IMT与吸烟组比较差异无统计学意义(P>0.05)。哈族的IMT为(0.78±0.21)mm,汉族为(0.76±0.28)mm,维族为(0.66±0.26)mm,3个民族间差异均有统计学意义(P<0.05)。各民族不同性别颈动脉IMT均随年龄增长而增加。IMT随吸烟情况、性别、民族、年龄、收缩压、舒张压、血糖及三酰甘油水平变化而变化(P<0.05)。结论:吸烟是新疆地区维、汉、哈3个民族成年人中IMT增厚的危险因素。Objective To investigate the association between smoking and carotid intima-media thickness in Han,Uygur and Hazakh adults in Xinjing,and difference of carotid intima-media thickness in smokers of three nationalities.Methods Four-stage random sampling method was used to select three groups of Han,Uygur and Hazakh adults aged over 35 years in Xinjiang.The numbers of male and female were similar.The distribution feature of carotid intima-media thickness was observed and compared in different smokers,nationalities,ages and genders.Multielement stepwise regression analysis was used to analyze the influencing factors of intima-media thickness.Results The carotid intima-media thickness of smoking groups and giving-up-smoking groups was thicker than that in nonsmoking groups after adjusting age,gender and body mass index by covariance analysis,and there were no significant differences between giving-up-smoking groups and smoking groups（P〈0.05）.The carotid intima-media thicknesses were（0.78±0.21）,（0.76±0.28） and（0.66±0.26）mm in Hazakh,Han,and Uygur population,which showed significant differences in three groups（P〈0.05）.The carotid intima-media thickness had the increasing trend with aging in all patients,and the intima-media thickness changed with the changes of smoking status,gender,nationality,age,systolic blood pressure,diastolic blood pressure,plasma glucose levels and triacylglycerol（P〈0.05）.Conclusion Smoking is a risk factor for increased carotid intima-media thickness in Han,Uygur and Hazakh adults.

关 键 词：颈动脉内中膜厚度 吸烟 流行病学研究 

分 类 号：R543.4[医药卫生—心血管疾病]