海柳挥发性成分的分析  

Analysis of volatile components of black coral

作　　者：白雪婷[1] 陈一村[1] 陈伟洲[2] 雷华平[3] 石刚刚[1] 

机构地区：[1]汕头大学医学院药理学研究室,广东汕头515041 [2]汕头大学海洋生物研究所,广东汕头515063 [3]中山大学生命科学学院,广东广州510275

出　　处：《癌变．畸变．突变》2011年第3期199-201,205,共4页Carcinogenesis,Teratogenesis & Mutagenesis

基　　金：国家自然科学基金项目(30973922);广东省自然科学基金团队项目(9351503102000001);广东省科技计划项目(2008B030301240;2010B030700043);广东省中医药局项目(2008162;2010408)

摘　　要：目的:提取分离海柳的挥发性成分并鉴定。方法:采用二氧化碳超临界萃取出海柳挥发性成分,再经气质联用分析,结合保留指数计算,鉴定其成分。结果:通过气质联用分析,共鉴定出15种化学成分,包括磷酸三乙酯、丁羟甲苯、雪松醇、棕榈酸、角鲨烯、胆甾醇等。这些成分多具有生物活性。结论:首次揭示海柳的挥发性成分,海柳所具有的功效可能与其含有的生物活性成分有关。OBJECTIVE：To investigate the volatile constituents of black coral（BC）.METHODS：The volatile constituents of BC were extracted by supercritical fluid extraction with carbon dioxide（CO_2-SFE）,separated and identified by gas chromatography-mass spectrometry（GC-MS）combined with retention index.RESULTS：In total,15 components were reliably identified in BC and found to be biologically active.These included triethyl phosphate, butylated hydroxytoluene,cedrol,n-hexadecanoic acid,squalene and cholesterol.CONCLUSION：It is the first time that volatile constituents of BC were presented.The functions of BC are related to the active chemical compositions.

关 键 词：海柳 二氧化碳超临界萃取 气质分析 保留指数 

分 类 号：R931.5[医药卫生—生药学]