细菌性阴道病联合检测技术在妊娠期妇女阴道感染诊断中的应用  

Application of combined detection technology of bacterial vaginosis in diagnosis of vaginal infection in pregnant women

作　　者：马健[1] 李超[1] 

机构地区：[1]四川省成都市锦江区妇幼保健院,610061

出　　处：《中国妇幼保健》2011年第18期2745-2747,共3页Maternal and Child Health Care of China

摘　　要：目的:探讨细菌性阴道病(BV)联合检测技术在妊娠期妇女阴道感染诊断中的应用价值。方法:选取2010年11月～2011年2月至成都市锦江区妇幼保健院门诊就诊的790例妊娠期妇女,其中早孕组360例、中孕组240例、晚孕组190例,采集阴道分泌物,测定pH值后分别进行生理盐水涂片,对假丝酵母菌、滴虫、清洁度的检测和过氧化氢浓度、唾液酸酶和白细胞酯酶三项联合测定,妇科门诊非阴道炎患者(年龄≤40岁)220例进行相同的检查作为非孕组对照。结果:应用BV三项联合技术测定和湿片镜检发现妊娠组与对照非孕组的优势菌异常率分别为44.05%和28.18%,BV感染率分别为20.76%和19.09%,外阴阴道假丝酵母菌(VVC)感染率分别为16.58%和13.18%,滴虫感染率分别为0.89%和2.73%,BV合并VVC感染率分别为9.49%和7.73%。结论:三项联合检测技术操作简单、快速、准确,从功能学分别反映阴道优势菌、致病菌的指标,可与白带常规镜检互补,建议可作为阴道分泌物常规检查和产前阴道分泌物筛查。Objective：To explore the application value of combined detection technology of bacterial vaginosis in diagnosis of vaginal infection in pregnant women.Methods：790 pregnant women were selected from outpatient department of the hospital from November 2010 to February 2011,including 360 women in early pregnancy group,240 women in middle pregnancy group and 190 women in late pregnancy group;vaginal secretions were collected,smear of normal saline was conducted after detecting pH value.Candida,trichomonas and cleanliness detection combined with hydrogen peroxide concentration,sialidase and leukocyte esterase detection were performed.220 cases without bacterial vaginosis（≤40 years） receiving the same examinations were selected from gynecological outpatient as control group.Results：The abnormal rates of predominant bacteria in pregnancy group and control group were 44.05% and 28.18%,respectively;the infection rates of bacterial vaginosis in pregnancy group and control group were 20.76% and 19.09%,respectively;the infection rates of vulvovaginal candidiasis（VVC） in pregnancy group and control group were 16.58% and 13.18%,respectively;the infection rates of trichomonas in pregnancy group and control group were 0.89% and 2.73%,respectively;the infection rates of bacterial vaginosis combined with VVC were 9.49% and 7.73%,respectively.Conclusion：The combined detection technology is simple,quick and accurate,which can reflect the indexes of vaginal predominant bacteria and pathogenic bacteria in terms of function,and the method is complementary with regular colposcopy of leukorrhea,it is recommended that the method can be used as regular examination of vaginal secretions and prenatal screening of vaginal secretions.

关 键 词：阴道感染 过氧化氢浓度 唾液酸酶 白细胞酯酶 

分 类 号：R711.31[医药卫生—妇产科学]