慢性阻塞性肺疾病体质指数与焦虑抑郁的相关性  

Correlation between anxiety or depression and body mass index in patients with chronic obstructive pulmonary disease

作　　者：林敏[1] 魏立平[1] 周伯荣[1] 康闪闪[1] 朱恬华[1] 邓燕华[1] 曾青山[1] 

机构地区：[1]广州医学院第三附属医院呼吸内科,广州510150

出　　处：《广东医学》2011年第11期1417-1420,共4页Guangdong Medical Journal

基　　金：广东省科技计划项目(编号:20070402029)

摘　　要：目的探讨稳定期COPD患者体质指数(BMI)与焦虑抑郁的相关性。方法 72例稳定期COPD患者作为研究对象,按BMI分为低BMI组(45例)和非低BMI组(27例),分别测量身高及体重、肺功能检查、汉密顿抑郁量表(HAMD)、汉密顿焦虑量表(HAMA)问卷调查;分析BMI和各项指标的相关性。结果低BMI组患者肺功能较非低BMI组下降,HAMD、HAMA评分高于正常BMI组,差异有统计学意义(P<0.05);相关性分析表明焦虑、抑郁与BMI相关。结论 COPD患者营养状况越差,焦虑、抑郁的发生率就越高,焦虑、抑郁症状就越严重。Objective To study the relationship between BMI and anxiety or depression in patients with stable COPD. Methods Seventy - two patients with stable COPD were enrolled and divided into two groups according to BMI ： underweight group （45 cases） and non -low BMI group （27 cases）. Height, weight, pulmonary function, Hamilton Depression Rating Scale （HAMD） and Hamilton Anxiety Scale （HAMA） were assessed in all subjects. Correlation analysis was performed between BMI and psychiatric indexes. Results Significantly lower pulmonary function and higher scores of HAMD and HAMA were revealed in underweight group, when comparing with those in non - low BMI group （ P 〈 0.05 ）. Furthermore, significant correlations were found between BMI and anxiety （r = -0.463, P =0.01 ）, or depression （r = - 0.528,P = 0. 01 ）. Conclusion The low nutrition status of COPD patients is significantly associated with risks of anxiety and depression.

关 键 词：肺疾病 慢性阻塞性 体重指数 焦虑 抑郁 

分 类 号：R173[医药卫生—妇幼卫生保健]