Remote postconditioning induced by brief pulmonary ischemia and reperfusion attenuates myocardial reperfusion injury in rabbits  

作　　者：TANG Yan-hua XU Jian-jun LI Ju-xiang CHENG Xiao-shu 

机构地区：[1]Department of Cardiothoracic Surgery [2]Department of Cardiology, Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi330006, China

出　　处：《Chinese Medical Journal》2011年第11期1683-1688,共6页中华医学杂志（英文版）

摘　　要：Background The lung is one of the most important organs that are sensitive to ischemia. We hypothesized that remote postconditioning （RPostC） induced by brief occlusion and reperfusion of the pulmonary artery could attenuate myocardial reperfusion injury. Methods Thirty rabbits were randomized into three groups. Group ischemia-reperfusion （IR） （n=10） were anesthetized rabbits subjected to 30-minute occlusion of the left anterior descending coronary artery followed by 180-minute reperfusion.Background The lung is one of the most important organs that are sensitive to ischemia. We hypothesized that remote postconditioning （RPostC） induced by brief occlusion and reperfusion of the pulmonary artery could attenuate myocardial reperfusion injury. Methods Thirty rabbits were randomized into three groups. Group ischemia-reperfusion （IR） （n=10） were anesthetized rabbits subjected to 30-minute occlusion of the left anterior descending coronary artery followed by 180-minute reperfusion.

关 键 词：remote postconditioning endothelial nitric oxide synthase reperfusion injury 

分 类 号：R686[医药卫生—骨科学]