甘草及其活性成分的表面活性比较研究  

Comparative analysis on surface activity of Glycyrrhiza Radix and its active ingredients

作　　者：马鸿雁[1] 李霞[1] 李楠[1] 高亚男[1] 

机构地区：[1]成都中医药大学药学院,四川成都610075

出　　处：《现代药物与临床》2011年第3期227-229,共3页Drugs & Clinic

基　　金：成都中医药大学校基金资助项目(310-041)

摘　　要：目的研究甘草及其活性成分的表面活性,为更合理地研究甘草中成分的增溶能力提供参考。方法在不同温度下,采用Wilhelmy吊片法测定溶液的表面张力和溶液的临界胶束浓度(CMC)。结果分析了溶液的表面活性效能、效率和表面过剩浓度,甘草水煎液表面活性较好。结论甘草中除皂苷组分具有表面活性外,其他组分对表面活性有贡献。Objective To study the surface activity of Glycyrrhiza Radix and its active ingredients, and provide the reference for solubilizing capabilities of Glycyrrhiza Radix and its active ingredients. Methods The Wilhelmy plate method was used to determine the surface tension of the aqueous solutions of monoammonium glycyrrhizinate, glycyrrhizinate; saponins in Glycyrrhiza Radix, and Glycyrrhiza Radix, and the critical micelle concentration （CMC） at different temperatures. Results The efficiency, efficacy and surface concentration were analyzed, and the surface activity of the solution of Glycyrrhiza Radix was better. Conclusion There are other components to contribute to the surface activity of Glycyrrhiza Radix solutions except saponins in Glycyrrhiza Radix.

关 键 词：甘草 甘草酸单铵盐 甘草皂苷 表面活性 临界胶束浓度 

分 类 号：R282.71[医药卫生—中药学]