牛蒡子饮片和牛蒡子现代饮片RP-HPLC指纹图谱对比研究  

Comparative Study on RP-HPLC Fingerprints of Traditional Decoction Pieces and Modern Decoction Pieces of Fructus Arctii

作　　者：刘婧[1] 傅超美[1] 毛茜[1] 马雪玮[1] 林俊芝 许丽佳[1] 

机构地区：[1]成都中医药大学药学院,四川成都611137

出　　处：《成都大学学报（自然科学版）》2011年第2期104-107,共4页Journal of Chengdu University（Natural Science Edition）

摘　　要：通过对比分析牛蒡子饮片及牛蒡子现代饮片指纹图谱,探讨两者之间品质是否存在差异.采用RP-HPLC指纹图谱技术,对牛蒡子饮片及牛蒡子现代饮片进行指纹图谱研究,并建立共有模式,同时,采用"中药色谱指纹图谱相似度评价系统"对所得图谱进行相似度分析.结果表明:牛蒡子饮片和牛蒡子现代饮片所测定的色谱图中,指纹图谱共有峰均有7个,各组分得到很好的分离,相似度评价均大于0.90;牛蒡子饮片和牛蒡子现代饮片指纹图谱之间无明显差异,品质基本一致.To explore whether the quality of traditional decoction pieces and modern decoction pieces of Fructus Arctii was different or not,their RP-HPLC fingerprints were compared.RP-HPLC fingerprint technology was adopted to study the two kinds of fingerprints and establish a common mode.Similarity evaluation system for chromatographic fingerprint of TCM was utilized to analyze the obtained fingerprint.The results show that there are 7 common peaks which are well separated in the two chromatograms and the similarity is greater than 0.90.It is concluded that there was no significant difference between the fingerprints of traditional decoction pieces and modern decoction pieces of Fructus Arctii,whose quality are basically consilient.

关 键 词：牛蒡子 现代饮片 RP-HPLC 指纹图谱 

分 类 号：R284.2[医药卫生—中药学] R285.5[医药卫生—中医学]