纳滤体器件在生物分子分离中的研究进展  

Progress of biomolecule separation by nanofilter in experimental and theoretical research

作　　者：夏广杰[1] 汪蓉[1] 

机构地区：[1]南京大学化学化工学院,高分子科学与工程系,配位化学国家重点实验室,南京微结构国家实验室,南京210093

出　　处：《科学通报》2011年第18期1411-1418,共8页Chinese Science Bulletin

基　　金：国家自然科学基金(20874046,21074053);国家重点基础研究发展计划(2010CB923303)资助项目

摘　　要：人类对生物体系的理解取决于生物分子高效准确的挑选和分离.随着纳滤体器件(Nanofilter)的蓬勃发展,其在生物分子分离领域的应用受到了广泛关注,并成为无胶体系生物分子分离的热点之一.本文结合纳滤体器件的产生及发展,从纳滤体器件的设计及理论模型两方面重点阐述了纳滤体器件在生物分子分离方面的研究进展,并对纳滤体器件的计算机模拟进行了讨论.近年来,相比于传统的生物分子分离方法,纳滤体器件所具有的优势日益突出.而纳米技术的进一步发展,也使其具有很好的应用前景.Knowledge of biological systems critically depends on the ability to sort and separate biomolecules efficiently and accurately. The development of the nanofilter and its applications to separation of biomolecules have attracted much research attention, and the nanofilter has become one of the hot spots in gel-free separation of biomolecules. The technique and theoretical models are discussed to reveal the progress that has been made in biomolecule separation using nanofilters. Computer simulation of the nanofilter is also discussed. In recent years, the advantages of nanofilters compared with traditional separation methods for biomolecules have become increasingly apparent. Moreover, with the progress of nanotechnology the nanofilter will have commercial applications.

关 键 词：纳滤体器件 生物分子 分离 

分 类 号：Q503[生物学—生物化学]