超声二维应变技术对冠心病患者左心室扭转运动的研究  

Two-Dimensional Strain Imaging for Investigating Left Ventricular Torsion in Patients with Coronary Artery Disease

作　　者：吴灵敏[1,2] 杨莉[1] 方思华[1] 邱琼[1] 

机构地区：[1]中山大学附属第二医院心内科,广州市510120 [2]浙江省金华市中心医院

出　　处：《中国超声医学杂志》2011年第6期518-521,共4页Chinese Journal of Ultrasound in Medicine

基　　金：广东省医学科研基金(No.A2008184)

摘　　要：目的运用超声二维应变技术检测冠心病患者左心室扭转运动的变化并探讨其临床意义。方法冠心病组52例,对照组31例。常规测定左室射血分数(LVEF)。采集高频二维动态图像,运用二维应变软件获得左心室短轴基底部、心尖部旋转角度峰值(Rot-base、Rot-apex)及左心室扭转角度峰值(LV-tor)。结果冠心病组与对照组的Rot-base、Rot-apex及LV-tor均无显著性差异(P>0.05);亚组分析显示:3支病变亚组的Rot-base、Rot-apex及LV-tor显著低于对照组(P<0.05),而LVEF与对照组无显著性差异(P>0.05)。结论范围较广的心肌缺血可引起左心室扭转运动减弱;应用二维应变技术检测左心室扭转运动变化可早期发现冠心病患者左心室功能受损。Objective To detect left ventricular torsional changes in patients with coronary artery disease（CAD） by two-dimensional strain imaging, and to study its clinical implication. Methods Fifty-two patients with coronary artery disease and 31 control subjects were enrolled. LVEF was measured with Simpson method using two-dimentional echocardiography. High frame rate two-dimensional dynamic images were recorded from the left ventricular short-axis views at the basal and apical levels. Using two-dimensional strain software,The peak basal and apical rotation （Rot- base, Rot-apex） in basal and apical plane and peak left ventricular torsion（LV-tor）were caculated using Echo PAC software. Results Rot-base, Rot-apex and LV-tor were not significantly different between coronary artery disease and control groups （P〉0.05）. Compared with the control group, Rot-base, Rot-apex and LV-tor were significantly lower in the 3-vessel disease subgroup （P〈0.05） ,No significant difference was found for LVEF in ACD and contral groups （P〉0.05）. Conclusions Left ventricular torsion was impaired in patients with extensive myocardial ischemia. Left ventricular torsional changes detected by two-dimensional strain imaging may be used as an early index of left ventricular dysfunction in patients with coronary artery disease.

关 键 词：超声心动图 二维应变 冠心病 左心室扭转 

分 类 号：R445.1[医药卫生—影像医学与核医学] R541.4[医药卫生—诊断学]