胃癌声像图特点与组织学分化程度的相关性  

Correlation of Ultrasonographic Feature with Histological Differentiation in Gastric Carcinoma

作　　者：徐春媚[1] 董晓秋[1] 王思明[1] 郑宏群 

机构地区：[1]哈尔滨医科大学附属第四医院超声科,哈尔滨市150001 [2]肿瘤科

出　　处：《中国超声医学杂志》2011年第6期536-539,共4页Chinese Journal of Ultrasound in Medicine

基　　金：哈尔滨市科技创新人才研究专项资金项目(No.2006RFQXS077)

摘　　要：目的探讨胃癌声像图特点与术后病理组织学分化程度之间的相关性。方法将82例经手术病理证实的胃癌患者分为低分化组和分化型组,进行回顾性分析。对超声测量的病灶长度、厚度进行统计学分析,并计算两组病灶长度、厚度的95%可信区间;对其中的67例进展期胃癌进行Borrmann分型后分析。结果低分化组病灶长度及厚度均大于分化型组,两组差异有统计学意义(P<0.05、P<0.05);病灶长度的95%可信区间,低分化组为5.5～7.5 cm,分化型组为2.4～4.2 cm;病灶厚度的95%可信区间,低分化组为1.4～1.8 cm,分化型组为0.8～1.1 cm;BorrmannⅠ型、Ⅱ型在分化型组中的构成比高于低分化组,Ⅲ型、Ⅳ型的构成比低于低分化组,两组差异有统计学意义(P<0.05)。低分化组中长度大于5.5 cm者最多,占53.7%(29/54),厚度大于1.4 cm者最多,占55.6%(30/54),分化型组中长度小于4.2 cm者最多,占64.3%(18/28).厚度小于1.1 cm者最多,占60.7%(17/28),结合Borrmann分型,分化型组和低分化组符合率分别提高到71.4%(20/28)和63.0%(34/54)。结论超声图像上胃癌病灶的长度、厚度与组织学分化程度相关,术前对胃癌组织学分化程度进行初步判断具有可行性,结合Borrrnann分型,有助于判断。Objective To investigate the correlation of ultrasonographic feature with histological differentiation in gastric carcinoma. Methods Statistical analysis was made on the length and thickness of tumor between group of poorly differentiated carcinoma and group of differentiated carcinoma respectively by retrospectively study. Also 95 reliable range of the length and thickness of tumor in the two groups were calculated. Statistical analysis was made on Borrmann type between two groups of 67 cases of advanced gastric carcinoma. Results The length and thickness of the poorly differentiated group was higher than those of differentiated group, and there were a significant differences be tween the two groups （P〈0.05 ,P〈0.05） ; 95% reliable range of the length of tumor was 5.5～7.5 cm in poorly dif ferentiated group, and 2.4～4.2 cm in differentiated group; 95% reliable range of the thickness of the tumor was 1.4～1.8 cm in poorly differentiated group, and 0.8～ 1.1 cm in differentiated group. The highest pathologic accuracy is 64.3% which length is below 4.2 cm, and 60.7% which thickness is below 1.1 cm in differentiated group;The highest pathologic accuracy is 53.70/00 which length is over 5.5 cm, and 55.6% which thickness is over 1.4 cm in poorly differentiated group. Considering about Borrmann type, the accuracy were raised to 71.4 ~ and 63.0 %in differentiated group and poorly differentiated group respectively. Conclusions There were correlation between the length and thickness of gastric carcinoma and histological differentiation degree,it has the possibility to make a judgment on the histological differentiation degree in the tumor preoperatively, and Borrmann type will be helpful.

关 键 词：超声 胃癌 病灶长度 病灶厚度组织学分化程度 BORRMANN分型 

分 类 号：R445.1[医药卫生—影像医学与核医学] R735.2[医药卫生—诊断学]