超声造影在肝癌术后患者中早期诊断复发的应用  被引量:8

Contrast-Enhanced Ultrasound In Early Diagnosis of Recurrence After Hepatectomy for Hepatocellular Carcinoma

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作  者:崔贤[1] 李开艳[1] 张喜君[1] 

机构地区:[1]华中科技大学同济医学院附属同济医院超声影像科,武汉市430030

出  处:《中国超声医学杂志》2011年第6期539-542,共4页Chinese Journal of Ultrasound in Medicine

摘  要:目的探讨超声造影对肝癌术后患者肝内微小占位病变(直径≤2 cm)的诊断价值。方法采用低机械指数实时谐波超声造影技术,对常规超声不能确定的48例肝癌术后患者肝内的54个微小占位病变进行超声造影检查。48例患者均有近期血清甲胎蛋白(AFP)检测结果,对AFP不高的患者同时行增强CT或磁共振检查。最终将超声造影结果与治疗前后AFP的变化、增强CT或磁共振诊断、随访6个月以上的结果进行对比。结果超声造影诊断正确51个病灶,其中复发病灶37例43个,硬化结节8例8个。3例3个超声造影诊断为复发,治疗前AFP升高,治疗后未下降。超声造影的诊断符合率为94.4%(51/54)。结论超声造影对复发性肝癌的早期诊断具有重要意义,为肝癌术后患者的动态随诊提供可靠的依据。Objective To evaluate the value of contrast-enhanced ultrasound (CEUS) on the diagnosis of microhepatic lesions(≤2cm) after hepatectomy for hepatocellular carcinoma(HCC). Methods A total of 48 patients with 54 nodules on ultrasound were observed and analyzed with real-time harmonic ultrasonographic imaging under a low mechanical index CEUS. All the 48 patients tested the serum levels of a-fetoprotein(AFP), and the ones with normal level of AFP performed contrast-enhanced helieal computed tomography(CECT) or magnetic resonance imaging(MRI). The final diagnosis was based on interpreting of examinations with the change of AFP, CECT or MRI, and follow up da- ta. Results 51 nodules including 37 patients with 43 HCC and 8 patents with 8 benign nodules were correctly diag nosed by CEUS. 3 lesions in 3 cases were diagnosed as recurrence by CEUS, but their AFP increased before treatment, didnCt decrease after treatment. The diagnostic accuracy of CEUS was 94.4% (51/54). Conclusions The CEUS is valuable for early diagnosis of recurrence hepatocelluar carcinoma(RHCC), which provide a way for monitoring patients after hepatectomy for HCC.

关 键 词:肝肿瘤 超声检查 造影剂 

分 类 号:R445.1[医药卫生—影像医学与核医学] R735.7[医药卫生—诊断学]

 

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