羧酸制备伯胺的方法综述  

Review of the Preparation of Primary Amine from Carboxylic Acid

作　　者：连建伟[1] 夏建陵[1,2] 黄坤[1] 李梅[1] 杨小华[1] 

机构地区：[1]中国林业科学研究院林产化学工业研究所生物质化学利用国家工程实验室国家林业局林产化学工程重点开放性实验室江苏省生物质能源与材料重点实验室,江苏南京210042 [2]中国林业科学研究院林业新技术研究所,北京100091

出　　处：《林产化学与工业》2011年第3期115-121,共7页Chemistry and Industry of Forest Products

基　　金："十一五"国家科技支撑计划资助(2009BADB1B10);国家自然科学基金青年科学基金项目(31000280)

摘　　要：系统综述了羧酸制备伯胺的各种常用方法,包括羧酸通过酰胺化制备伯胺和羧酸还原为醇、酮或醛后再经氨解反应得到伯胺,以及羧酸直接转化为伯胺的方法,并指出了各种方法的优点以及存在的问题。最后,对羧酸制备伯胺的方法进行了展望。In this paper,various common methods to preparing primary amine from carboxylic acid were systematically summarized.They included primary amine prepared through amidation of carboxylic acid,carboxylic acid firstly reduced to alcohol,ketone and aldehydes and followed by ammonolysis for preparing primary amine,and direct conversion of carboxylic acid.Meanwhile,the advantages and problems existing in each method were pointed out.Finally,the preparation of primary amine from carboxylic acid were prospected.

关 键 词：羧酸 伯胺 酰胺 制备 

分 类 号：TQ351[化学工程] O621.3[理学—有机化学]