超声实时组织弹性成像在甲状腺弥漫性疾病中的初步应用  

Preliminary application of ultrasound real-time elastography in diagnosis of thyroid diffuse disease

作　　者：石秀英[1] 艾红[1] 王娟[1] 

机构地区：[1]西安交通大学第一附属医院超声影像科,710061

出　　处：《中华超声影像学杂志》2011年第6期515-518,共4页Chinese Journal of Ultrasonography

摘　　要：目的探讨超声实时组织弹性成像对甲状腺弥漫性疾病的诊断价值。方法采用主成分分析对123例甲状腺弥漫性疾病患者和42例甲状腺正常者的11个弹性定量参数进行综合分析，把综合评价函数值命名为硬度指数（stiffness index，SI）来反映甲状腺疾病组织的弹性信息，并用方差分析比较SI在各组间的差异。结果慢性淋巴细胞性甲状腺炎SI为86．37±20．45，亚急性甲状腺炎sI为86．14±19．95，原发性甲状腺功能亢进SI为54．68±21．69，正常对照组SI为41．34±15．59。慢性淋巴细胞性甲状腺炎、亚急性甲状腺炎、原发性甲亢与正常对照组之间SI差异有统计学意义（P〈0．05）；原发性甲亢与慢性淋巴细胞性甲状腺炎、亚急性甲状腺炎之间的SI差异有统计学意义（P〈0．05）；慢性淋巴细胞性甲状腺炎与亚急性甲状腺炎之间SI差异无统计学意义（P〉0．05）。结论实时超声弹性成像可间接反映甲状腺病变组织的硬度，对甲状腺弥漫性疾病具有一定的诊断价值。Objective To explore the diagnosis value of ultrasound real-time elastography in thyroid diffuse diseases. Methods Eleven elastic quantitative parameters of 123 patients with thyroid diffuse diseases and 42 healthy volunteers obtained from the ultrasound real-time elastography were analyzed with principal components analysis to attain a comprehensive evaluation value which was named stiffness index （SI）, reflecting the organization elastic information of different thyroid diffuse diseases. SI among each group was compared by ANOVA. Results Chronic lymphocytic thyroiditis SI was 86.37 ± 20.45, subacute thyroiditis SI was 86.14 ± 19.95, primary hyperthyroidism SI was 54.68 ± 21.69, normal control group SI was 41.34± 15.59, respectively. The SI between chronic lymphocytic thyroiditis, subacute thyroiditis, primary hyperthyroidism and normal controls had significant statistical differences （P〈 0.05）, the SI between primary hyperthyroidism and chronic lymphocytic thyroiditis, subacute thyroiditis had significant statistical differences （ P 〈0.05）, the SI between chronic lymphocytic thyroiditis and subacute thyroiditis had no significant statistical difference （ P 〉0.05）. Conclusions Ultrasound real-time elastography could indirectly reflect the stiffness information of thyroid lension tissue and have a certain degree of diagnosis value in thyroid diffuse disease.

关 键 词：超声检查 甲状腺疾病 弹性 

分 类 号：R445.1[医药卫生—影像医学与核医学]