血吸虫病疾病负担的研究I慢性血吸虫病健康寿命损失年的计算与评价  

Burden of disease in schistosomiasis japonica I Calculation and evaluation of years lived with disability of chronic schistosomiasis

作　　者：贾铁武[1] 孙乐平[2] 洪青标[2] 邓瑶[2] 张功华[3] 汪昊[3] 易平[4] 郭家钢[1] 周晓农[1] 

机构地区：[1]中国疾病预防控制中心寄生虫病预防控制所,上海200025 [2]江苏省血吸虫病防治研究所 [3]安徽省血吸虫病防治研究所 [4]湖南省血吸虫病防治所

出　　处：《中国血吸虫病防治杂志》2011年第3期243-248,共6页Chinese Journal of Schistosomiasis Control

基　　金：国家科技支撑计划(2009BAI78B07);国家自然科学基金重大项目(30590373);国家重大科技专项(2008ZX10004-11)

摘　　要：目的探讨慢性血吸虫病疾病负担的评价指标及其计算方法。方法根据2004-2005年在湖区两县开展的血吸虫病流行病学专题调查数据分别计算居民不同年龄组、性别和流行村类型等的专属血吸虫病患病率。根据专题调查得出的年龄别伤残权重,按年龄和性别分层,求得健康寿命损失年(YLD)及YLD率,并推算两县的总体YLD。结果当涂县总体YLD为1056.26人年,汉寿县总体YLD为3967.43人年。两县一类村YLD占慢性血吸虫病疾病负担的37.95%,高年龄组和男性的YLD率较高。与非流行区比较,慢性血吸虫病给流行区人口平均增加了4.398人年/1000人(当涂县)和1.505人年/1000人(汉寿县)的疾病负担。结论对慢性血吸虫病YLD进行评价,有助于确定重点干预地区和人群,并可为干预措施的效果评价等提供新指标。Objective To discuss the evaluation index of the disease burden of chronic schistosomiasis and its calculation methods. Methods The epidemiological data came from the thematic research carried out in two schistosome-endemic counties in lake areas between 2004 and 2005. The specific prevalence rates by age group, gender and endemic type were calculated. According to the age-specific disability weight obtained in the thematic research, the years lived with disability （YLDs） and the rates of YLD of stratified samples by age and gender, and the total YLDs of the two counties were calculated. Results The total YLDs were 1 056.26 and 3 967.43 person-years in Dangtu and Hanshou counties, respectively. The contributing rate of GradeⅠtype village to the total YLDs of two counties was 37.95% （40.08% in Dangtu and 37.39% in Hanshou）. For different stratums by age and gender, the older ones and male tended to have larger YLDs. Compared to the non-endemic areas, chronic schistosomiasis brought an average extra of 4.398 and 1.505 years per 1 000 person to population in Dangtu and Hanshou counties, respectively. Conclusion The evaluation to YLDs of chronic schistosomiasis is helpful for prioritizing intervention areas and population, as well as providing a new index for the evaluation of effectiveness of control measures.

关 键 词：慢性血吸虫病 疾病负担 伤残调整寿命年 伤残权重 健康寿命损失年 

分 类 号：R532.21[医药卫生—内科学]