精神分裂症与血清同型半胱氨酸水平关系的研究  

THE RELATIONSHIP BETWEEN SCHIZOPHRENIA AND SERUM HOMOCYSTEINE LEVEL

作　　者：胡国艳[1] 刘学军[1] 

机构地区：[1]广州市精神病医院,广东广州510370

出　　处：《现代医院》2011年第6期20-21,共2页Modern Hospitals

摘　　要：目的探讨同型半胱氨酸与精神分裂症的相关性。方法检测319例精神分裂症患者和136例健康体检者血清同型半胱氨酸水平,并对结果进行对比分析。结果精神分裂症患者血清同型半胱氨酸水平(17.71±8.16μmol/L)明显高于正常对照组(11.92±3.25μmol/L),差异有统计学意义。其中男性患者血清同型半胱氨酸水平(18.84±8.24μmol/L)高于女性患者(16.04±7.77μmol/L),差异也有统计学意义。结论精神分裂症血清同型半胱氨酸水平升高,并与性别有关,可能是其发生发展的危险因素之一。Objective To approach the relationship between schizophrenia（SP） and homocysteine（Hcy） leve1.Methods The Hcy level of 319 cases with schizophrenia and 136 normal individuals（control group） was detected by one-step immunoassay.Results The mean level of Hcy in the schizophrenia group was obviously higher than that in the control group（p0.05）.The mean level of Hcy in male patients was higher than that in female patients,the difference has statistics significance.Conclusion The level of serum homocysteine is increased in patients with schizophrenia,and have a correlation with sex.Homocystaine may be one of the risk factors of schizophrenia.

关 键 词：精神分裂症 同型半胱氨酸 

分 类 号：R714.246[医药卫生—妇产科学]