西升麻中三萜皂苷类分离鉴定及药材质量标准研究  

Isolation and Identification of Triterpenoid Saponins and Quality Standards of Cimicifugae Rhizome

作　　者：靳波[1,2] 刘友平[1,2] 陈鸿平 赵祎姗[1,2] 彭月[1,2] 

机构地区：[1]成都中医药大学药学院,成都611137 [2]中药资源系统研究与开发利用省部共建国家重点实验室培育基地,成都611137

出　　处：《中国实验方剂学杂志》2011年第13期103-106,共4页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：质检公益性行业科研专项(2007GYB075-2);校学生科研实践创新课题(013-011-39)

摘　　要：目的:完善西升麻药材质量标准。方法:首次以分离的三萜皂苷类结合酚酸类建立定性及定量测定方法。结果:鉴定分离出的三萜皂苷类为升麻苷H-1;测定阿魏酸、异阿魏酸和咖啡酸含量之和为0.22%～1.90%,升麻苷H-1含量为0.10%～1.28%。结论:本试验结果能全面的反映西升麻药材内在质量,且稳定,简单,可行,为西升麻药材质量标准的完善提供参考。Objective：To improve the quality standard of Cimicifugae Rhizome.Method： Quantitative and qualitative determination methods were established by phenolic acids and separated triterpenoid saponins firstly.Result： The separated triterpenoid saponin was Cimicifuga glycosides H-1.The sum of ferulic acid,ferulic acid and caffeic acid was 0.22%-1.90%.The content of Cimicifuga glycosides H-1 was 0.10%-1.28%.Conclusion： The tests fully reflected the intrinsic quality of Cimicifuga Rhizome and the methods established are stable,simple,and suitable for the quality improvement of Cimicifugae Rhizome.

关 键 词：西升麻 升麻苷H-1 总酚酸 质量标准 

分 类 号：R284.1[医药卫生—中药学]