芳香化湿法为主干预湿浊型糖耐量低减的临床研究  

Clinical Investigation of Treatment of Eliminating Dampness with Aromatics on Damp-pathogen Syndrome in Impaired Glucose Tolerance

作　　者：周劲刚[1] 

机构地区：[1]桂林医学院附属医院,广西桂林541001

出　　处：《中国实验方剂学杂志》2011年第13期210-212,共3页Chinese Journal of Experimental Traditional Medical Formulae

摘　　要：目的:观察芳香化湿法为主干预湿浊型糖耐量低减(IGT)的疗效。方法:患者随机分为2组,在饮食控制、运动治疗和糖尿病教育等基础治疗的同时,治疗组(中药组)40例,予芳香化湿法治疗;对照组40例,予盐酸二甲双胍肠溶片,疗程均为6个月。比较治疗前后的空腹血糖(FPG)、餐后2 h血糖(2 h PG)、空腹血清胰岛素(FINS)、血脂、胰岛素抵抗指数等指标的变化。结果:用药6个月后,治疗组降血糖疗效总有效率87.5%,与对照组总有效率85%疗效相当。2组患者治疗前后体重指数(BMI)、血脂水平无显著性差异。2组均有明显的降血糖作用,且治疗组有较好的改善临床症状和胰岛素抵抗的作用。结论:芳香化湿法为主的中药干预湿浊型糖耐量低减,能明显增强胰岛素敏感性,可逆转糖耐量低减。Objective：To observe the effect of treatment of eliminating dampness with aromatics on damp-pathogen syndrome in impaired glucose tolerance（IGT）.Method：Patients were randomly assigned to two groups.All were treated with diet controlling,exercise treatment and diabetes millitus knowledge education.The 40 patients in the treatment group were treated by treatment of eliminating dampness with aromatics and the 40 patients in the control group were given metformin hydrochloride enteric-coated tablets.All for 6 months.Before and after treatment,fastig plasma glucose（FPG）,two hour plasma glucose（2 h PG）,fasting insulin（FINS）,blood fat of all the patients were detected,HOMA-IR was calculated.Result： All patients were treated 6 months later,at the effect decreasing blood glucose,the total effective rate were 87.5% in the treatment group.the total effective rate were 85% in the control group,they were the same effect.Before and after treatment,no significant differences were found between the two groups at BMI and blood lipid level.The two groups had obvious function of decreasing blood glucose.In addition,there was better function of improving clinic symptom and insulin resistance in the treatment group.Conclusion：The Chinese herbal medicine of eliminating dampness with aromatics on damp-pathogen syndrome in IGT can obviously enhance the insulin sensitivity.It can also to reverse IGT.

关 键 词：芳香化湿法 湿浊 糖耐量低减 

分 类 号：R287[医药卫生—中药学]