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作 者:尤炜[1] 轧春妹[1] 张平[1] 刘学兰[1] 陈颖杰[1]
出 处:《解放军护理杂志》2011年第11期42-43,共2页Nursing Journal of Chinese People's Liberation Army
基 金:天津市卫生局科研基金资助项目(05KYZ96)
摘 要:目的探讨HBsAg阳性产妇所产新生儿股静脉取血的适宜时间,以期为预防新生儿感染提供依据。方法 1999年10月至2010年1月,天津市传染病医院住院及门诊HBsAg阳性产妇所产足月新生儿21 348例,按随机数字表法将21 348例新生儿分为观察组(10 826例)与对照组(10 522例)。观察组新生儿于出生后2 h至4周经股静脉取血检测乙型肝炎5项和HBVDNA定量,对照组新生儿于出生后4~52周经股静脉取血检测相同项目,比较两组新生儿一次针刺取血的成功率。结果观察组新生儿一次针刺取血成功率明显高于与对照组新生儿,差异有统计学意义(χ2=233.868,P〈0.01)。结论新生儿出生4周内静脉取血检测乙型肝炎五项和HBVDNA定量更容易操作,且可以尽早地为临床提供新生儿HBV感染的相关信息,对乙型肝炎阻断治疗的实施意义重大。Objective To explore the collection time of femoral vein blood in neonates of HBsAg-positive puerpera so as to provide the evidence for protecting infections of neonates.Methods From October 1999 to January 2010,21348 full-term neonates were delivered by HBsAg-positive mother in our inpatient and outpatient department.The 21348 neonates were randomized into observation group(n=10 826) and control group(n=10 522).The neonates in the observation group were collected of femoral vein blood to test hepatitis B makers and HBV-DNA between 2 h and 4 w after birth.While the neonates in the control group were collected of femoral vein blood for the same test between 4 w and 52 w after birth.Comparison was conducted on the one-time success rate of acupuncture for blood collection.Results The one-time success rate for taking blood of the newborns of the observation group was significantly higher than that of the control group(χ^2=233.868,P0.01).Conclusion Collection of femoral vein blood of the newborns within 4w after birth is more convenient for five tests of Hepatitis B and quantitative HBVDNA test,with timely clinical information of neonates with HBV infection,which is of clinical significance for blocking hepatitis B.
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