新生儿高胆红素血症血尿β_2微球蛋白研究  

The study on β_2-microglobulin of blood and urin for neonates with hyperbilirubinemia

作　　者：孙树萍[1] 武丽霞[1] 张曦[1] 韩秀玲[1] 

机构地区：[1]包头医学院第二附属医院,内蒙古包头014030

出　　处：《基层医学论坛》2011年第19期583-584,共2页The Medical Forum

摘　　要：目的探讨新生儿高胆红素血症血、尿β2微球蛋白的变化及临床意义。方法分别测定40例新生儿高胆红素血症患儿血、尿β2微球蛋白,并与30例生理性黄疸新生儿进行对照。结果新生儿高胆红素血症组患儿血、尿β2微球蛋白水平均明显高于生理性黄疸组患儿(P<0.01)。结论新生儿高胆红素血症患儿存在肾功能损伤,血、尿β2微球蛋白水平可以早期敏感地判断新生儿肾功能的损伤程度。Objective To study the fluctuations of β2-microglobulin of blood and urin in neonates with hyperbilirusinemia and its clinical significance.Methods β2-microglobulin in blood and urine of 40 neonates with hyperbilirubinemia and 30 neonates with physiological icterus were tested respectively and the results of both growps were analyzed and compared.Results The level of β2-microglobulin in blood and urine in neonates with hyperbilirubinemia was significantly higher than that in neonates with physiologic icterus（P0.01）.Conclusion Children withNeonatal hyperbilirubinemia had damage of kidney function,Blood and urine β2 microglobulin levels could be early sensitive to judge the damage of neonatal renal function.

关 键 词：血Β2-微球蛋白 尿Β2-微球蛋白 高胆红素血症 新生儿 

分 类 号：R722.1[医药卫生—儿科]