达芬霖喷剂治疗鼻炎的疗效观察  

The curative effect of daphnlin spray on treating rhinitis

作　　者：乐建新[1] 黄选兆[1] 檀慧芳[1] 

机构地区：[1]同济医科大学附属协和医院耳鼻咽喉科,武汉430022

出　　处：《临床耳鼻咽喉科杂志》1999年第10期454-456,共3页Journal of Clinical Otorhinolaryngology

摘　　要：目的:观察达芬霖喷剂在治疗鼻炎中消除或缓解鼻塞症状的效果,探讨治疗鼻炎的有效药物。方法:对慢性单纯性鼻炎、肥厚性鼻炎、常年性变应性鼻炎患者共105例,分别用达芬霖喷剂(达芬霖组)和麻黄素喷剂(麻黄素组)进行治疗和疗效对比。结果:达芬霖组的总有效率为90.9%;麻黄素组为69.3%。达芬霖起效时间72.2%在1min以内,维持时间70.4%的患者在5h以上;而麻黄素组起效时间68.7%为1～3min,维持时间71.8%在3h以内。在治疗慢性单纯性鼻炎、常年性变应性鼻炎1周后,达芬霖组所测鼻阻力值低于麻黄素组(P<0.05)。结论:达芬霖喷剂缓解鼻塞迅速,维持时间长,疗效显著,安全性好,明显优于麻黄素喷剂。Objective:To observe the effect of Daphnlin spray on decongesting rhinocleisis and to search effective drugs for treating rhinitis.Method:105 patients collected from chronic simple rhinitis,chronic hypertrophic rhinitis and perennial allergic rhinitis were treated with daphnlin spray (daphnlin group) or ephedrine spray (ephedrine group).Result:The total efficiency of daphnlin group in treating rhinitis above is 90.9 % and that of ephedrine group ( 69.3 %) in 1 minute and for ephedrine group is mostly ( 68.7 %) between 1 to 3 minutes.The keeping curative effect time for daphnlin spray is mostly ( 70.4 %) above 5 hours and for ephedrine spray is mostly ( 71.8 %) in 3 hours.After a week,the nasal resistances are difference between daphnlin group and ephedrine group.Conclusion:Daphnlin spray is better than ephedrine spray in decongesting rhinocleisis,keeping curative effect and in safety,so daphnli is one kind of effective drugs in treating rhinitis.

关 键 词：达芬霖喷剂 鼻炎 药物疗法 

分 类 号：R765.210.5[医药卫生—耳鼻咽喉科]