长期接触低浓度二硫化碳对作业工人心血管系统的影响  

Effects of long term exposure to lower concentration of carbon disulfide on cardiovascular system of workers in a viscose rayon factory

作　　者：毕勇毅[1] 谭晓东[1] 王福元[1] 孔丹莉[1] 汪春红[1] 闫俊[1] 李阳[1] 

机构地区：[1]湖北医科大学卫生学教研室,武汉430071

出　　处：《卫生研究》1999年第5期259-260,共2页Journal of Hygiene Research

基　　金：比利时( A B O S B V1346)和湖北省教委重点课题基金

摘　　要：对某化纤厂９９名长期接触低浓度二硫化碳（ Ｃ Ｓ２ ）作业工人和２８名同厂非 Ｃ Ｓ２ 作业工人的血压、血脂和心电图进行了流行病学横断面调查。结果表明：接触组和对照组舒张压和压缩压差别无统计学差异；接触组脂蛋白（ａ）［ Ｌｐ（ａ）］浓度明显高于对照组，其它血脂指标均无统计学差异；接触组出现心电图异常的危险性是对照组的１１倍，但无统计学差异。提示 Ｌｐ（ａ）可作为对心血管方面 Ｃ Ｓ２毒作用敏感的健康监测指标。An epidemiological cross sectional study was conducted on 99 workers exposed to lower concentration of carbon disulfide in a viscose rayon factory for a long time and 28 non exposed ones in the same factory. Blood pressure, serum lipoproteins and electrocardiograph were detected. The results showed that neither diastolic blood pressure nor systolic one between exposed group and control group was obviously different All indicators of serum lipids and lipoproteins were not significantly different except the lipoprotein(a) of exposed group was significantly higher than that of control group, and the risk of abnormal electrocardiogram in the workers exposed to carbon disulfide was 1 1 times of those non exposed ones but with no statistical significance. The results suggest that lipoprotein(a) can be used as a sensitive indicator for the cardiotoxic effects of carbon disulfide.

关 键 词：二硫化碳 心血管系统 脂蛋白 作业工人 

分 类 号：R135.14[医药卫生—劳动卫生] R54[医药卫生—公共卫生与预防医学]