氯乙酸甲酯为萃取剂的液-液半微萃取与胶束电动色谱耦联富集分离中性化合物  

Methyl Chloroacetate as Extraction Solvent for Coupling Liquid-liquid Semimicroextraction with Micellar Electrokinetic Chromatography for the Separation of Neutral Compounds with Concentration Enhancement

作　　者：唐婧[1] 郑胜彪[1] 朱金坤[1] 王田霖[2] 

机构地区：[1]安徽科技学院理学院,凤阳233100 [2]上海大学化学系,上海200444

出　　处：《高等学校化学学报》2011年第7期1488-1491,共4页Chemical Journal of Chinese Universities

基　　金：安徽科技学院引进人才基金项目(批准号:ZRC2009239)资助

摘　　要：建立了液-液半微萃取与胶束电动色谱耦联的富集分离方法,以氯乙酸甲酯为萃取剂,通过萃取剂的柱上分解来富集分离中性化合物.选取苯酮类化合物作为模型,将水中的苯酮类化合物通过液-液半微萃取进入氯乙酸甲酯相中,氯乙酸甲酯相直接进入胶束电动色谱中分离.对于苯乙酮(C8)、苯丁酮(C10)和苯戊酮(C11)的检出限分别为50,50和100μg/L(S/N≥3),三者的富集因子达到63～151.本方法设备简单,省时且操作简便.用此方法对环境雌激素叔丁基苯酚(4-tBP)和双酚A(BPA)进行加标回收实验,回收率分别为99.87%和102.8%.该方法具有用于实际环境样品分析的潜力.This paper reports the use of methyl chloroacetate（MCA） as an extraction solvent for coupling liquid-liquid semimicroextraction（LLsME） with micellar electrokinetic chromatography（MEKC） through on-capillary decomposition for the separation of neutral compounds with concentration enhancement.Alkylphenones butyrophenone,valerophenone and acetophenone were chosen as modeling compounds.Aqueous samples of the alkylphenones were extracted by LLsME into MCA.The organic phase was directly subjected to separate by MEKC.The detection limits（S/N≥3） were 50,50 and 100 μg/L for butyrophenone,valerophenone and acetophenone in water,respectively,and the concentration factors of the extraction were in a range of 63 to 151-fold in terms of peak area.The method developed has no requirement for any special experimental apparatus other than a basic CE setup and is time-saving and easy-ope-rated.Recoveries of 4-t-BP and BPA in drink water were examined.The recoveries were obtained as 99.87% and 102.8%,respectively.Therefore,it would be readily acceptable for routine analysis,especially for environmental samples.

关 键 词：液-液半微萃取 胶束电动色谱 氯乙酸甲酯 苯酮 富集 

分 类 号：O657.8[理学—分析化学]