西南远志中一个新的呫吨酮苷  

A new xanthone glycoside from Polygala crotalarioides

作　　者：周凌云[1] 周凡蕊[2] 华燕[2] 

机构地区：[1]皖南医学院,安徽芜湖241002 [2]西南林业大学,云南昆明650224

出　　处：《中草药》2011年第7期1261-1263,共3页Chinese Traditional and Herbal Drugs

基　　金：西南林业大学重点基金项目(200704Z)

摘　　要：目的对西南远志Polygala crotalarioides的化学成分进行研究。方法运用硅胶、RP-18及Sephadex LH-20等柱色谱方法分离西南远志的化学成分,通过理化常数和MS、1H-NMR、13C-NMR等波谱数据鉴定化合物的结构。结果从西南远志中分离得到2个化合物,分别为1,3,6-三羟基-7-甲氧基呫吨酮-4-β-D-呋喃芹糖-(1→2)-[β-D-呋喃芹糖(1→6)]-β-D-吡喃葡萄糖苷(1)和1,3,6-三羟基-7-甲氧基呫吨酮-4-β-D-呋喃芹糖-(1→6)-β-D-吡喃葡萄糖苷(2)。结论化合物1为新化合物,命名为西南远志呫吨酮苷F(crotalarioides xanthone F)。Objective To study the chemical constituents of Polygala crotalarioides.Methods Two compounds were isolated by various chromatographies over silica gel column,reverse phase column（RP-18）,and Sephadex LH-20.Their structures were elucidated by spectroscopic analysis and chemical means.Results A new compound,1,3,6-trihydroxy-7-methoxyxanthone 4-β-D-apiofuranosyl-（1→6）-[β-D-apiofuranosyl-（1→2）]-β-D-glucopyranoside（1）,along with another compound,1,3,6-trihydroxy-7-methoxyxanthone-4-β-D-apiofuranosyl-（1→6）-β-D-glucopyranoside（2） was isolated from P.crotalarioides.Conclusion Compound 1 is a new compound named crotalarioides xanthone F.

关 键 词：西南远志 西南远志呫吨酮苷F 远志属 1 3 6-三羟基-7-甲氧基呫吨酮-4-β-D-呋喃芹糖-(1→2)-[β-D-呋喃芹糖(1→6)]-β-D-吡喃葡萄糖苷 1 3 6-三羟基-7-甲氧基呫吨酮-4-β-D-呋喃芹糖-(1→6)-β-D-吡喃葡萄糖苷 

分 类 号：R284.1[医药卫生—中药学]