2010年我院细菌耐药性监测  

Monitoring of bacterial drug resistance in our hospital in 2010

作　　者：游先辉[1] 

机构地区：[1]成都市青白江区人民医院,四川青白江610300

出　　处：《现代医药卫生》2011年第14期2116-2118,共3页Journal of Modern Medicine & Health

摘　　要：目的:调查2010年我院临床分离细菌的分布和耐药特征,指导临床合理用药。方法:采用纸片扩散法进行药敏试验并对肠杆菌科细菌进行ESBLs检测,用WHONET5.5软件进行数据分析。结果:2010年我院共分离细菌1 044株,其中革兰阴性杆菌718株,占68.8%,革兰阳性球菌326株,占31.2%。大肠埃希菌和金葡菌分别占革兰阴性杆菌和革兰阳性球菌的首位。大肠埃希菌、肺炎克雷伯菌中ESBLs的检出率分别为18.9%、10.6%。葡萄球菌属中MRSA和MRCNS的检出率分别为34.5%和43.2%。结论:我院患者分离的细菌耐药性非常严重,应加强监测,指导临床合理使用抗菌药物。Objective：To investigate the distribution and antibiotic resistance characteristics of clinical bacterial isolates from our hospital in 2010 to guide clinical rational drug use.Methods：The disk diffusion method was adopted for performing the drug susceptibility test and ESBLs for detecting Enterobacteriaceae with Whonet5.3 software for data analysis.Results：1044 strains of bacteria were isolated from our hospital in year 2010,including 718 strains（68.8%） of Gram-negative bacteria and 326 strains（31.2%） of Gram-positive cocci.Escherichia coli and Staphylococcus aureus occupied the first place for Gram-negative bacilli and gram-positive cocci respectively.The detection rates of ESBLs in Escherichia coli and Klebsiella pneumoniae were 18.9% and 10.6% respectively.The detection rates of MRSA and MRCNS in Staphylococcus were 34.5% and 43.2% respectively.Conclusion：Bacteria isolated from the patients in our hospital have very serious drug resistance.Monitoring should be strengthened to guide rational use of antimicrobial drugs.

关 键 词：细菌耐药性 抗菌药物 革兰阳性球菌 革兰阴性杆菌 

分 类 号：R9[医药卫生—药学]