维生素C对老年2型糖尿病患者记忆功能障碍的影响  

Impact of vitamin C on memory impairment in elderly type 2 diabetes mellitus

作　　者：易莲[1] 张松筠[2] 

机构地区：[1]河北省邯郸市第一医院内分泌二科,056002 [2]河北医科大学第二附属医院内分泌科,石家庄050005

出　　处：《疑难病杂志》2011年第2期104-106,共3页Chinese Journal of Difficult and Complicated Cases

摘　　要：目的观察维生素C对老年2型糖尿病患者记忆功能障碍的影响。方法将纳入患者随机分为2组。对照组给予常规治疗(包括饮食调整、适量运动、合理选择双胍类和/或磺脲类降糖药);观察组在常规治疗基础上加用维生素C 0.2g每日3次,疗程1年。治疗前后分别行简易精神状态量表(MMSE)、蒙特利尔认知功能(MoCA)量化并评分。结果治疗后2组MMSE及MoCA(对照组注意力除外)得分在治疗后均得到明显改善(P<0.01),且观察组优于对照组(空间定位除外)。结论维生素C作为一种抗氧化剂,能明显改善老年2型糖尿病患者的记忆功能障碍。Objective To observe the therapeutic effects of vitamin C in type 2 diabetes mellitus with memory impairment. Methods All patients involved were divided into two groups;the control group（patients were administrated with traditional treatment,including diet modification,proper exercise,reasonable choices of metformin and/or sulfonylurea） and the treatment group（patients were administrated with vitamin C 0.2g,3 times a day additionally）.The MMSE and MoCA tests were performed before and after 1 year treatment.Results The MMSE and MoCA scores（except attention in control group） were improved in both the treatment group and control group（P〈0.05）,and the results were more obviously in treatment group（except of ability of spatial localization,P〈0.01）.Conclusion As a kind of antioxidant,the vitamin C could improved the memory impairment in elderly type 2 diabetes patients.

关 键 词：糖尿病 2型 记忆功能 认知功能 维生素C 

分 类 号：R587.1[医药卫生—内分泌]