军事应激对军人部分生化生理指标的影响  

The influence of military stress on some physiological and biochemical indexes

作　　者：郭学青[1] 高宏伟[1] 张岩[2] 路路[1] 彰颖[1] 刘杰[1] 

机构地区：[1]北京军区总医院263临床部检验科,北京101149 [2]北京军区总医院神经外科实验室,北京100070

出　　处：《国际检验医学杂志》2011年第11期1173-1175,共3页International Journal of Laboratory Medicine

摘　　要：目的选择与应激相关的生化生理指标,研究并探讨军事应激对军人部分生化生理指标的影响。方法随机选取参加阅兵军事人员60例,采用酶联免疫吸附(ELISA)法分别检测阅兵前、后军人免疫相关指标和氧化还原过程相关指标的血清水平,并对军事心理应激引起的标志物显著性改变的机制进行探讨。结果军人血清肿瘤坏死因子α、白细胞介素6、促肾上腺皮质激素释放因子、前列环素、胃泌素和超氧化物歧化酶水平显著升高。结论军事应激状态对机体免疫系统、神经内分泌系统和氧化还原过程具有重要的影响,肿瘤坏死因子α、白细胞介素6、促肾上腺皮质激素释放因子、前列环素、胃泌素和超氧化物歧化酶等可作为观察机体应激状态的生化标志物。Objective To explore the influence of the military stress on some stress related blood physiological and biochemical indexes. Methods 60 soldiers,who took part in a military parade,were selected at random and detected for the changes of the serum levels of immunity and oxidation-reduction system related indexes by enzyme linked immunosorbent assay（ELISA）. The further analysis was performed to investigate the mechanism of the changes of serum markers induced by military stress. Results Six of all serum markers increased significantly,including tumor necrosis factor α（TNF-α）,interleukin-6 （IL 6）, corticotropin-releasing factor （CRF） ,prostacyclin（PGI） ,gastrin（Gas） and superoxide dismutase（SOD）. Conclusion The military stress can affect immunity,endocrine and oxidation-reduction system. TNF-α,IL-6 ,CRF,PGI,Gas and SOD can be used as biomarkers to monitor the stress status of body.

关 键 词：军事医学 应激 心理学 生化生理指标 

分 类 号：R82[医药卫生—临床医学]