胺碘酮治疗老年心房纤颤的疗效及安全性观察  

作　　者：曹丹阳[1] 曹晶晶[1] 周冬翠[1] 武云涛[1] 陈艳梅[1] 毕磊[1] 

机构地区：[1]北京解放军北京军区总医院,100700

出　　处：《浙江临床医学》2011年第6期612-614,共3页Zhejiang Clinical Medical Journal

摘　　要：目的探讨胺碘酮对老年阵发性房颤治疗的效果和安全性。方法观察分析40例老年阵发性房颤患者胺碘酮治疗的效果和药物副作用。结果胺碘酮治疗显效率为55．0％，有效率为32．5％，无效率为12．5％；发生甲状腺功能减退7例，未发生甲状腺功能亢进、肺纤维化、色素沉着。结论胺碘酮应用于老年人房颤有效、安全，但需密切观察甲状腺功能和对肺的毒性作用。Objective To study tile efficacy and safety of Amiodarone for treating atrial fibrillation in old patients. Methods We retrospectively reviewed 40 elderly cases of atrial fibrillation, amiodarone was administered 0.6 g/day initially, then gradually reduced to 0. 2 g/day for maintainance, the curative effect and the side effects of amiodarone in treatment of atrial fibrillation was observed. Results The efficiency of amiodarone treatment was 55%, laseris 32. 5%, inefficient to 12. 5%. Simultaneous hypothyroidism occurred in 7 cases, thyroid function in hyperthyroidism, pulmonary fibrosis, pigmentation did not happen in all cases. Conclusions Amiodarone for treating atrial fibrillation in old patients is effective and safe.

关 键 词：老年人 心房纤颤 胺碘酮 

分 类 号：R541.750.5[医药卫生—心血管疾病]