脐动脉血流测定联合无负荷试验对子痫前期中胎儿预后的评估  

Fetal nonstress test combined with umbilical artery doppler velocimetry for assessment of fetal prognosis in preeclampsia

作　　者：光瑾[1] 丛林[1] 

机构地区：[1]安徽医科大学,合肥230022

出　　处：《安徽医学》2011年第6期730-732,共3页Anhui Medical Journal

摘　　要：目的探讨子痫前期患者脐动脉血流S/D,阻力指数(RI)、搏动指数(PI)水平的测定及其联合无负荷试验对评估胎儿宫内状况及预后的价值。方法观察记录64例子痫前期患者的脐动脉血流参数S/D值、PI、RI和无负荷试验以及新生儿出生时Apgar评分,新生儿体质量和胎盘质量及羊水性状等,回顾性分析血流参数,无负荷试验与围生儿结局的关系。结果①重度子痫前期S/D、RI、PI比值明显高于正常组,统计结果差异有统计学意义(P<0.05),轻度子痫前期组与正常组比较也有增高趋势,差异有统计学意义(P<0.05);②重度子痫前期的新生儿出生时Apgar评分低于正常组,新生儿体质量和胎盘质量较正常组下降,统计结果差异有统计学意义(P<0.05)。但上述变化在轻度子痫前期组表现不明显(P>0.05)。③NST可疑型和无反应型组脐动脉血流S/D≥3发生率比NST反应型组明显增高。④S/D<3和S/D≥3两组在NST阳性反应中差异有统计学意义(P<0.05)。结论子痫前期患者脐动脉血流联合无负荷试验可预示病情的严重程度及胎儿宫内情况,为临床及时干预提供依据。Objective To assess fetus intrauterine conditions and the value of the prognosis with umbilical arterial blood S/D,RI,PI level and combined with fetal nonstress test in preeclampsia patients.Methods Fetal umbilical arterial blood flow parameters S/D value,pulse index（PI）,resistive index（RI） combined with fetal nonstress test were used in 64 preeclampsia women and newborn Apgar scores,Neonatal weight and placenta weight and amniotic fluid properties were recorded.Then retrospectively analyzed the relationship between the blood flow parameters,fetal nonstress test and Perinatal infant.Results ①Umbilical arterial blood S/D,RI,PI level significantly were higher than that of normal in severe preeclampsia group,statistical results had significant difference（P0.05）.The scores in mild preeclampsia group were also statistically significant higher compared with normal group,statistically significant（P0.05）.②newborn Apgar scores,Neonatal weight and placenta weight in severe preeclampsia group were significantly lower（P0.05） than that of normal group,But No significant differences were found in mild preeclampsia group（P0.05） ③Umbilical arterial blood S/D≥3 in NST suspicious type and no reactive groups significantly higher than in NST reaction type.④There were significant difference between S/D 3 group and S/D≥3 group in NST positive reaction type（P 0.05）.Conclusion Preeclampsia patients umbilical arterial blood combined with fetal nonstress test can indicate the severity of the illness of the fetus and the fetal status,and can provide the basis for clinical timely intervention.

关 键 词：彩色多普勒 子痫前期 脐动脉血流速度 无负荷试验 

分 类 号：R714.5[医药卫生—妇产科学]