儿童青少年超重、肥胖与代谢综合征的关系  

Correlation between overweight,obesity and metabolic syndrome in adolescents

作　　者：席倩[1] 许华山[2] 吴志昊[1] 王佩[1] 张翼[1] 崔巍[1] 

机构地区：[1]安徽省蚌埠市第三人民医院内分泌科,233000 [2]蚌埠医学院精神医学系,安徽蚌埠233030

出　　处：《蚌埠医学院学报》2011年第6期602-605,共4页Journal of Bengbu Medical College

基　　金：安徽省蚌埠市2007年科技计划项目(医疗卫生4号)

摘　　要：目的:分析儿童青少年超重、肥胖与代谢综合征(metablolic syndrome,MS)的流行特点,探讨肥胖与MS的关系。方法:对蚌埠市2007年自愿参加学生健康体检的921名7～18岁学生进行身高、体重、腰围、臀围、血压测量,随机分为体重正常组334名、超重组253名、肥胖组334名。同时测定空腹时静脉血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇、空腹血糖(FPG)、尿酸和超敏C反应蛋白,并进行比较。结果:共检出MS 128名,其中体重正常组3名(0.9%),超重组30名(11.9%),肥胖组95名(28.4%),3组MS发病率差异有统计学意义(P<0.01);3组间男生及女生MS检出率差异均有统计学意义(P<0.01);超重组和肥胖组中高血压、腹型肥胖、腰臀比、腰高比、低HDL-C、高TG、高FPG发生率均显著高于体重正常组(P<0.05～P<0.01);除超重组中TC、肥胖组与超重组FPG和TC与体重正常组比较差异无统计学意义(P>0.05)外,其余各指标各组间差异均有统计学意义(P<0.05～P<0.01)。结论:青少年随着体重的增加,MS及MS危险因素显著增加。Objective：To analyze the features of metabolic syndrome （MS） in adolescents, and to explore the correlation between obesity and MS so as to prevent obesity and MS in children. Methods：Nine hundred twenty-one students aged from 7 - 18 were selected from the primary schools and middle schools in Bengbu city. The height, weight, waist circumference, hip circumference, blood pressure, TC,TG,HDL-C,LDL-C,FPG,UA and hs-CRP of the children were measured and compared. Results： MS was detected in 128 of the students. Among them, three cases were in the normal weight group （0.9 % ）, 30 in the obesity group （ 11.9% ） and 95 in the overweight group（28.4% ）. The difference was significant among the three groups（ P 〈 0.01 ）. The rate of MS differed significantly between the male and the female students（P 〈 0.01 ）. The prevalence of high blood pressure, central obesity, WHR, WHtR, low HDL-C, high TG and high FPG in the overweight group and the obese group were significantly higher than that in the normal weight group （ P 〈 0.05 - P 〈0.01 ）. The FPG and TC had no significant differences between the over -weight group and the normal group（ P 〉 0. 05 ） , while other factors were significantly different among the three groups（ P 〈 0.05 - P 〈 0.01 ）. Conclusions：The prevalence and risk factors of MS increase along with the rise of body weight in the adolescents.

关 键 词：代谢综合征 儿童青少年 肥胖 

分 类 号：R589[医药卫生—内分泌]