广州市海珠区手足口病流行病学与临床资料分析  

Study on Epidemiological and Clinical Characteristics of Hand-foot-mouth Disease in Haizhu District of Guangzhou City

作　　者：陈欣欣[1] 王斌[1] 杜江[1] 赵宏[1] 纪国业[1] 余楠[2] 

机构地区：[1]南方医科大学珠江医院儿科,广东广州510282 [2]南方医科大学珠江医院检验科,广东广州510282

出　　处：《实用预防医学》2011年第6期1008-1011,共4页Practical Preventive Medicine

摘　　要：目的总结儿童手足口病(HFMD)临床表现和诊治体会,探讨其危险因素及对疗效影响。方法对HFMD患儿资料作回顾性总结分析及流行病学分析。结果普通病例组平均住院日与重症病例组比较差异有统计学意义(P<0.01);普通病例组与对照组之间,WBC比较差异无统计学意义(P>0.05)。LYM%和GRAN%的比较差异有统计学意义(P<0.01),重症病例组与普通病例组之间LYM%和GRAN%的比较差异有统计学意义(P<0.01)。急性期与恢复期患者LYM%、GRAN%、Mono%LYM%、GRAN%、Mono%比较差异均有统计学意义(P<0.01)。结论患者就诊时间越及时可以降低发展成为危重病人的风险。在临床应用中可加强对GRAN%这个易于检测的指标的认识,对病情进行病情观察、动态评估和预后判断,并以此作为手足口病患者短期内发展为危重病例的重要参考指标。Objective To evaluate the clinical phenotypes,diagnosis and treatment of the hand-foot-mouth disease（HFMD） in children,and to explore the impact of risk factors on its treatment course.Methods The clinical and epidemiological data from children with hand-foot-mouth disease were retrospectively analyzed.Results There were statistically significant differences in the mean days of hospital stay between children with simple HFMD syndromes and children with critical HFMD syndromes（P〈0.01）.There was no statistically significant difference in WBC between children with simple HFMD syndromes and healthy controls（P〈0.05）.The comparison of LYM% and GRAN% between children with simple HFMD syndromes and children with critical HFMD syndromes showed statistically significant differences（P〈0.01）.Conclusions To treat early may reduce the risk to become in critical stage of HFMD.GRAN% can be used to evaluate the condition of HFMD patients who may become critically ill and indicate favorable prognosis.

关 键 词：手足口病 危险因素 诊断 

分 类 号：R512.5[医药卫生—内科学]