2009-2011年衡阳市流行性感冒病原学监测分析  被引量:13

Etiological Analysis of Influenza Monitoring Data in Hengyang from 2009 to 2011

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作  者:楼萍[1] 李哲婷[1] 刘英豪[1] 颜淑妩[1] 邓婵[1] 

机构地区:[1]湖南省衡阳市疾病预防控制中心,湖南衡阳421001

出  处:《实用预防医学》2011年第6期1022-1023,1027,共3页Practical Preventive Medicine

摘  要:目的分析衡阳市2009-2011年度流感病毒流行情况,了解病毒毒株的型别及变化特点,为预防和控制流感提供科学依据。方法采集流感样病例(ILI)的鼻咽拭子标本,采用狗肾细胞(MDCK)进行病毒分离和(或)RT-PCR方法检测病毒核酸,分离到的毒株采用血凝抑制实验(HI)进行流感病毒型别鉴定。结果 2009年3月-2011年2月共采集2 682份ILI咽拭子标本,采用病毒分离887份,分离到毒株116株,分离阳性率13.08%,其中季节性A(H1N1)亚型31株,季节性A(H3N2)亚型35株,B-victoria系36株,B-yamagata系6株,新甲型H1N1 8株;采用核酸检测2 143份,核酸阳性737份,阳性率34.39%,其中新甲型H1N1 543份,季节性A型146份,季节性B型48份。结论 2009年3月-2011年2月流感毒株各型别阶段性交替形成优势株。全年皆有流感样病例,夏季高峰较明显。2009年是流感大流行年,9月新甲型H1N1的流行成为主导,并在11-12月份达到流行高峰。为更好防控流感,及时掌握流行趋势,仍需加强监测。Objective To investigate the epidemic situation of influenza in Hengyang from 2009 to 2011,to analyze the types and change features of dominant circulating influenza viruses,and to provide a scientific base for prevention and control of influenza.Methods Throat swabs were collected from influenza-like illness(ILI) cases.The strains were isolated by Madin-Darby carine kidney(MDCK) cells and/or the nucleic acid of influenza viruses was detected by RT-PCR.The types of influenza virus were confirmed by hemagglutination inhibition test.Results Totally 2,682 throat swab specimens were collected from March,2009 to February,2010.Virus isolation was conducted in 887 ILI specimens,and 116 strains were isolated,with the isolated positive rate of 13.08%.Among them,31 strains were seasonal A(H1N1) subtype,35 were seasonal A(H3N2) subtype,36 were B-victoria system,6 were B-yamagata system,and 8 were the new strains of influenza H1N1.Nucleic acid testing was performed in 2,143 copies,and 737 copies were positive for nucleic acid,with the positive rate of 34.39%.Among them,543 were new influenza A(H1N1),146 were seasonal A,and 48 were seasonal B.Conclusions From March,2009 to February,2011,each type of influenza virus alternately became the dominant influenza strain of each stage.ILI cases occurred in each month,and the peak of the incidence was in summer.The 2009 influenza pandemic outbreak showed that novel influenza A H1N1 virus infection was predominant in September,and reached the peak in November and December.It is necessary to strengthen the surveillance so as to further preventing and controlling influenza and knowing the trends of the epidemic in time.

关 键 词:流行性感冒 监测 流感毒株型别 

分 类 号:R373.1[医药卫生—病原生物学]

 

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