钯催化Heck反应的研究进展  

Recent progress in palladium-catalyzed Heck reaction

作　　者：刘惠芳[1] 蔡正元[1] 史延慧[1] 

机构地区：[1]徐州师范大学化学化工学院,江苏徐州221116

出　　处：《徐州师范大学学报（自然科学版）》2011年第2期1-11,共11页Journal of Xuzhou Normal University(Natural Science Edition)

基　　金：国家自然科学基金资助项目(21071121);江苏省教育厅"青蓝工程"项目(08QLD006;08QLT001);徐州师范大学科研基金资助项目(KY2008104;KY2008103)

摘　　要：钯催化的Heck反应是一类构建新的C—C键的偶联反应,也是卤代芳烃烯基化的重要手段.近年来,Heck反应已成为催化领域和有机合成化学方面的研究热点之一,并已取得了很好的研究成果.本文综述了近几年新发现的均相和非均相体系中Heck反应的研究进展,其中均相催化体系按参与的配体不同,可分为含膦、氮、硫及含NHC配体的钯催化体系;非均相催化体系按固相载体的不同,可分为活性炭、金属氧化物、介孔材料、二氧化硅等负载型钯催化体系.Heck reactions are a sort of classical methodology of the vinylation of aryl halides for the construction of new C—C bonds.The new efficient catalysts for Heck reactions and the applications in organic synthesis have been developed greatly these years.This review summarizes the progression using palladium compounds as catalysts in Heck reactions,including homogeneous and heterogeneous palladium catalysts.Homogeneous catalyzed system includes the palladium catalyst system with phosphoric,sulphur,nitrogen compounds and NHC as ligands;heterogeneous palladium catalyzed system can be divided with different carriers,including activated carbon,metal oxides,mesoporous supports and modified silica etc..

关 键 词：HECK反应 C—C键偶联 钯催化剂 

分 类 号：O621.25[理学—有机化学]