肺癌患者凝血系统功能的相关性研究  

Correlative Studys of Coagulant System Function in Patients with Lung Cancer

作　　者：张咏梅[1] 刘艳[1] 毛毅敏[1] 

机构地区：[1]河南科技大学第一附属医院,河南洛阳471003

出　　处：《河南科技大学学报（医学版）》2011年第2期97-99,共3页Journal of Henan University of Science & Technology:Medical Science

摘　　要：目的研究肺癌患者凝血、抗凝、纤溶系统功能状态。方法我院2009年10月~2010年12月收治初诊肺癌患者109例,以53例健康人为对照组,进行凝血、抗凝血、纤溶系统功能指标检测和VTE的临床筛查,将结果进行统计学处理和分析。结果肺癌组凝血系统各项指标均显著高于对照组（P〈0.01）,抗凝血系统功能指标均显著低于对照组（P〈0.01）,纤溶系统活性显著低于对照组（P〈0.01）,经筛查肺癌患者的VTE发生率为14.6%。结论肺癌患者凝血系统的活性增高、抗凝血系统和纤溶系统的活性减低,存在高凝状态,而且导致肺癌患者存在高VTE发病率。Objective To study the state of coagulation,anticoagulant,fibrinolysis system function in patients with lung cancer. Methods We collected 109 cases who had just been diagnosed as lung cancer from October 2009~December 2010,53 cases were healthy controls,testing coagulation,anticoagulant,fibrinolysis system function,all the patient also needed the clinical VTE examining,the results were treated by statistics analysis. Results The lung cancer patient coagulation indexed were significantly higher than those of control group（P0.01）,anticoagulant system function indexes were significantly lower than those of the control group（P0.01）,fibrinolysis system activity significantly lower than in control group（P0.01）,The frequency that lung cancer patient had VTE was 14.6 percent. Conclusion Lung cancer patients coagulant function system activity is increased,anticoagulant system and fibrinolysis system activity is reduced,lung cancer patients has hypercoagulability state,which lead to the high incidence of VTE in lung cancer patients.

关 键 词：肺癌 凝血功能 静脉血栓栓塞症 

分 类 号：R543.31[医药卫生—心血管疾病]