硫代苷脲的合成及表征  

Synthesis and characterization of the thiourea glycosides

作　　者：杨琴[1] 杨永利[1] 李丹[1] 龙江风[1] 

机构地区：[1]西安建筑科技大学理学院,陕西西安710055

出　　处：《化学试剂》2011年第7期660-662,共3页Chemical Reagents

基　　金：西安建筑科技大学校基金资助项目(JC1010)

摘　　要：以硫脲、乙二醛、盐酸为原料合成了硫代苷脲,考察了不同反应条件对产物收率的影响。并通过1HNMR、LC、MS、IR、DTA及TGA对目标产物的结构和热稳定性进行了表征。研究表明,较佳合成工艺为:硫脲与乙二醛的物质的量之比为3∶1,pH为1.0,反应温度为80℃,反应时间5 h,盐酸浓度为8 mol/L,产率可达83.1%,纯度99.04%,产品在290℃升华。Thiourea glycosides was synthesized using thiourea,oxaldehyde and hydrochloric acid as raw materials.The yield was 83.1% and the purity was 99.04% when molar ratio of thiourea and glyoxal was 3∶1,pH was 1.0,reaction temperature was 80 ℃ and reaction time was 5 h.The sublimation temperature of products is 290 ℃.The structure and thermal stability of the thiourea glycosides were confirmed by 1HNMR,IR,LC,MS,DTA and TGA.

关 键 词：硫代苷脲 瓜环 合成 表征 

分 类 号：O621.3[理学—有机化学]