加压提取地榆根中黄酮成分的研究  

Extraction of Total Flavonoids from Sanguisorba officinalis Root by Pressurized Liquid Extraction

作　　者：于慧荣[1] 赵文英[1] 朱兆友[1] 

机构地区：[1]青岛科技大学化工学院,青岛266042

出　　处：《天然产物研究与开发》2011年第3期449-452,共4页Natural Product Research and Development

基　　金：青岛科技大学科研启动基金资助(qust20071217);山东省中青年科学家科研奖励基金(BS2009SW033)

摘　　要：研究加压提取地榆中黄酮的最佳提取工艺。探讨了乙醇浓度、料液比、粒径、提取压力、提取温度和提取时间6个因素对黄酮得率的影响,并通过正交试验优化,确定了加压提取地榆中黄酮的最佳条件。结果表明加压提取地榆中黄酮的最佳提取条件:浸提温度120℃,料液比为1∶20,提取溶剂为60%的乙醇,浸提时间为30min,浸提压力为5 kg/cm2,粒径为40目,在该条件下黄酮提取率可达17.35%。与回流提取法相比,加压浸提法可显著提高浸提率。The extraction process of flavonoids from Sanguisorba officinalis root using pressurized liquid extraction（PLE） was studied and compared with reflux extraction.Significant parameters affecting PLE procedure such as the concentration of ethanol,solid-liquid ratio, temperature,pressure,time,and material size were discussed and optimized by the orthogonal test.The results showed that the optimized conditions were as follows：the extraction solvent 60% ethanol water solution,the material size 40 mesh,ratio of mass of raw material to volume of extraction solvent 1：20,extraction temperature 120 ℃,extraction 30 min under 5.0 kg/cm2 of pressure.The recovery of extraction could reach 17.35%.Comparing with reflux extraction,PLE can obviously increase the recovery of extraction.

关 键 词：地榆根 黄酮 加压提取 

分 类 号：R284.2[医药卫生—中药学]