190例药物不良反应患者临床特点分析  

Analysis of 190 adverse drug reaction reports

作　　者：刘璟[1] 游庆霞[1] 地里夏提[1] 

机构地区：[1]兰州军区乌鲁木齐总医院药剂科,新疆乌鲁木齐830000

出　　处：《中国医药导报》2011年第20期187-189,共3页China Medical Herald

摘　　要：目的:对医院发生的190例药物不良反应(ADR)进行分析总结,了解医院发生不良反应的一般规律和特点,为临床合理用药提供建议。方法:采用回顾性分析方法对2009～2010年本科收到的190例ADR反应报表,分别从患者性别和年龄、给药途径、ADR出现的时间、ADR累及的器官或系统及临床表现等方面进行统计分析。结果:190例ADR中男女比例为1.31∶1。其中大于70岁年龄组发生ADR居首位,共65例,占34.21%。通过静脉滴注给药方式产生的ADR为155例,占81%。结论:应重视ADR的监测和报告工作,以减少ADR的发生,确保临床安全用药。Objective：To analyze the occurrence of adverse drug reactions（ADR） in our hospital in order to know the characteristics and regulars,and provide the reference of the reasonable clinical medicine use.Methods：190 ADR cases collected in our hospital between 2009 and 2010 were classified and analyzed statistically in respect of gender and age of patients,routes of administration,occurrence time of ADR,organs and systems involved and clinical manifestations,and so on.Results：In 190 cases ADR reports,the proportion of male were higher than that of female（1.31∶1）.And 65 cases showed ADR among the over 70-year-old group,amounted to 34.21%.Intravenous drip（155 cases,81%） was the main route of administration.Conclusion：More atteneion should be paid to the monitoring and reporting of ADR so as to lessen the occurrence of ADR and ensure safety and rationality of drug use in clinic.

关 键 词：药物不良反应 用药分析 临床特点 分析 

分 类 号：R28[医药卫生—中药学] R994[医药卫生—中医学]