射干提取物对小鼠免疫功能的影响  

Effect of Belamcanda chinensis Extract on Mouse Immune Function

作　　者：赵金明[1] 秦文艳[1] 齐越[1] 陈贺[1] 宋达夫[1] 李国信[1] 

机构地区：[1]辽宁省中医药研究院药理室,沈阳110034

出　　处：《实验动物科学》2011年第3期11-13,共3页Laboratory Animal Science

基　　金：国家重大新药创制-科技重大专项(No.2009ZX9103-330)

摘　　要：目的研究射干提取物对小鼠免疫功能的影响。方法以环磷酰胺制备小鼠免疫低下模型,测定腹腔注射印度墨汁后小鼠网状内皮细胞(RES,单核巨噬细胞)炭粒廓清指数,观察其对小鼠非特异性免疫功能的影响;通过测定正常小鼠血清溶血素水平观察射干提取物对小鼠体液免疫的影响。结果射干提取物可增强小鼠网状内皮细胞的吞噬功能;促进抗体溶血素的产生。结论射干提取物对非特异性免疫功能和特异性免疫功能都有增强的作用。Objective To evaluate the effect of Belamcanda chinensis extract on mouse immune function.Methods Immunosuppressive mouse model induced by cyclophosphamide was employed to determine the carbon clearance index of reticuloendothelial cell（RES,mononuclear macrophage） after peritoneal injection of the Indian ink,and the effect of Belamcanda chinensis extract on the nonspecific immune function was examined.The serum hemolysin level was tested to survey the effect of Belamcanda chinensis extract on the humoral immunity.Results Belamcanda chinensis extract could enhance the phagocytosis of the mouse reticuloendothelial cells,and the producing of hemolysin.Conclusion Belamcanda chinensis extract significantly improves nonspecific and specific immunologic function in mice.

关 键 词：射干提取物 免疫功能 炭粒廓清 血清溶血素 

分 类 号：R285.5[医药卫生—中药学]