新城疫F蛋白基因工程疫苗的研究现状  

Research Progresses on Genetically Engineering Vaccine of the Newcastle Disease Virus Fusion Protein

作　　者：陶静[1] 叶红[2] 

机构地区：[1]上海中信国健药业股份有限公司抗体药物国家工程研究中心,上海201203 [2]黄山学院生命与环境科学学院,安徽黄山245021

出　　处：《安徽农业科学》2011年第17期10468-10469,10482,共3页Journal of Anhui Agricultural Sciences

基　　金：安徽省高校自然科学研究项目(KJ2010B211)

摘　　要：新城疫(Newcastle disease,NDV)是当今世界上最严重的禽类传染病之一,被世界动物卫生组织(OIE)列为必须报告的传染病。同预防其他传染病一样,新城疫的主要防控手段仍是免疫接种。F蛋白是构成新城疫病毒(NDV)致病性的分子基础之一。综述了国内外新城疫F蛋白基因工程疫苗的研究进展。Newcastle disease is one of t he most serious poultry diseases, especially in the field of poultry raising. It could bring great eco- nomic loss and it was defined as a rank A infectious disease by the OIE. Now the main method to prevent Newcastle disease is still the vaccine inoculation. NDV F protein constituted one of the molecular bases of pathogenicity. The research progresses on genetically engineering vaccine of the F protein of Newcastle disease virus were expounded.

关 键 词：新城疫 F蛋白 基因工程疫苗 

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