静脉丙种球蛋白治疗重症毛细支气管炎疗效分析  

The clinical efficacy of intravenous immune globulin treatments for severe bronchiolitis

作　　者：吴素虹[1] 王振开[1] 程宝金[1] 万瑜[1] 薛梅[1] 

机构地区：[1]南京医科大学附属常州市第二人民医院,江苏常州213003

出　　处：《实用临床医药杂志》2011年第11期143-145,共3页Journal of Clinical Medicine in Practice

摘　　要：目的观察静脉丙种球蛋白(IVIG)治疗重症毛细支气管炎的临床疗效。方法将重症毛细支气管炎患儿65例随机分为治疗组34例和对照组31例。对照组给予常规综合治疗,治疗组在此基础上加用静脉丙种球蛋白400 mg/(kg.d),连用3 d,观察2组疗效。结果 2组在紫绀、喘憋、肺部罗音消失时间及住院时间比较,差异有统计学意义(P<0.05)。2组总有效率比较,差异有统计学意义(P<0.05)。结论 IVIG治疗婴幼儿重症毛细支气管炎可缩短病程,疗效确切,可在临床推广应用。Objective To observe the clinical efficacy of intravenous immune globulin treatments for severe bronchiolitis.Methods Sixty-five patients with severe bronchiolitis were randomly divided into two groups.Thirty-four cases were in treatment group,and the rest 31 cases were in control group.The control group used regular treatment.The treatment group adopted IVIG（400 mg/（kg·d-1） in addition to the regular treatment,one injection a day for three consecutive days.Results Two groups were statistically different in purple gan,asthma suppress,lungs detect rales disappear time and hospitalization time comparison（P0.05）.The difference of total effectiveness of the two groups was statistically significant（P0.05）.Conclusion IVIG in treatment of infants with severe bronchiolitis can not only shorten the duration of symptoms,but also has definite effect.It can be clinically applied.

关 键 词：丙种球蛋白 毛细支气管炎 重症 

分 类 号：R725.6[医药卫生—儿科]