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机构地区:[1]广东医学院附属深圳福田人民医院儿科,广东深圳518033
出 处:《临床和实验医学杂志》2011年第13期1000-1001,共2页Journal of Clinical and Experimental Medicine
摘 要:目的评价早期监测新生黄疸早期干预治疗的临床效果。方法对新生儿进行黄疸动态监测,记录相关数据分析胆红素峰值出现的时间规律。对动态监测中发现的血清胆红素值超标的患儿给予早期干预治疗,并统计高胆红素血症的患病率与2003年全年未实施早期新生儿黄疸的动态监测与干预治疗时期的高胆红素血症患病率进行对比,以客观评定新生儿黄疸的动态监测与干预治疗的意义。结果对照组高胆红素血症发生率为36.93%,观察组为15.21%;对照组胆红素脑损伤的发生率为4.05%,观察组无脑损伤病例报告。结论动态监测可尽早发现新生儿血清胆红素水平的异常,为尽早干预治疗提供了保障。早期干预治疗极大地降低了高胆红素血症的患病率,有效预防新生儿胆红素脑损伤的发生。Objective To assess the clinical effect of dynamic monitoring of early neonatal jaundice and its clinical effect for early intervention.Methods The data of jaundice monitoring in delivery of newborns in this hospital,the time for occurrence of peak in serum level of bilirubin and dynamic monitoring of serum level of bilirubin were recorded and analyzed.The early intervention was given to children with excessive serum bilirubin and the incidence of hyperbilirubinemia was recorded.The incidence rate of hyperbilirubinemia was compared with that in the year of 2003 without implementation of early neonatal jaundice and dynamic monitoring of hyperbilirubinemia,and objective assessment of the significance of dynamic monitoring and early intervention was discussed.Results The incidence rate of hyperbilirubinemia in control group was 36.93%,and that in observation group was 15.21%.The incidence rate of brain impairment by bilirubin in control group was 4.05% and there was no brain impairment caused by bilirubin occurred in observation group.Conclusion Dynamic monitoring can early detect the abnormal level of bilirubin in neonatal serum,and it can guarantee the early therapeutic intervention for this disease.Early intervention can greatly reduce the incidence of hyperbilirubinemia in neonates and effectively prevent the occurrence of brain impairment by bilirubin in neonates.
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