重症监护病房常见病原菌调查分析  

Common pathogens in intensive care unit

作　　者：秦桂英[1] 邱隆敏[1] 杨泽敏[1] 龙盛双[1] 谢容[1] 

机构地区：[1]遵义医学院附属医院院感科,贵州遵义563003

出　　处：《中华医院感染学杂志》2011年第14期3061-3063,共3页Chinese Journal of Nosocomiology

摘　　要：目的对重症监护病房(ICU)住院患者各类感染性标本病原菌分布和药物敏感性进行回顾性调查分析,为指导临床合理用药,减少耐药菌产生,及时采取有效的隔离措施,降低医院感染,提高医疗质量提供指导依据。方法对2009年4月-2010年3月ICU住院患者各类感染性标本分离的328株病原菌资料进行回顾性分析。结果 ICU患者共送检标本1320份,阳性328份,阳性率24.85%,主要来源于痰液、尿液、血液,分别占81.40%、5.18%、5.18%;医院感染病原菌以革兰阴性菌为主,占71.95%,革兰阳性菌占16.16%,真菌占11.89%;大肠埃希菌中产ESBLs的菌株占78.95%,金黄色葡萄球菌中MRSA占97.67%。结论重症监护病房的病原菌以铜绿假单胞菌、鲍氏不动杆菌以及金黄色葡萄球菌为主,并且对多种药物耐药,临床上要引起高度重视。OBJECTIVE To retrospectively analyze the distribution and antimicrobial susceptibility of pathogens in various infections samples of the intensive care unit （ICU） patients and to provide guidance for guiding clinical rational use of drug, decreasing resistant bacteria, taking timely and effective quarantine measures; reducing nosocomial infections and improving medical quality. METHODS A total of 328 strains of pathogens in various infections samples of 404 inpatients of intensive care unit （ICU） from Apr 2009 to Mar 2010 were retrospectively analyzed. RESULTS The original bacteria samples from sputum, urine and blood accounted for 81.40%, 5.18% and 5.18%, respectively. The samples of the positive rate was 24.85 %,The distribution of nosocomial infection accounted for 71.95% Gram-negative bacteria, Gram-positive bacteria accounted for 16. 16%, ESBL production among E. coli strains accounted for 78. 95% of Staphylococcus aureus, MRSA accounted for 97. 67%, fungi accounted for 11.89 % CONCLUSION Pseudomonas aeruginosa , Acinetobacter baumannii and Staphylococcus aureus are the dominant pathogens with the character of multidrug resistance in ICU. We should pay close attention to them in clinical therapy.

关 键 词：重症监护病房 病原菌 药物敏感试验 

分 类 号：R378[医药卫生—病原生物学]