老年患者下呼吸道酵母样真菌感染的临床分析  

Clinical analysis of lower respiratory tract infection caused by candida in geriatric inpatients

作　　者：范晓云[1] 汪浩[1] 王聪慧[1] 武晓兰[1] 谭红霞[1] 沈继录[2] 

机构地区：[1]安徽医科大学第一附属医院老年呼吸内科,安徽合肥230022 [2]安徽医科大学第一附属医院检验科,安徽合肥230022

出　　处：《中华医院感染学杂志》2011年第14期3069-3071,共3页Chinese Journal of Nosocomiology

基　　金：安徽省卫生厅医学科研项目资助(09B095);安徽省高校自然科学研究项目资助(KJ2011a176)

摘　　要：目的探讨老年患者酵母样真菌社区与医院感染临床特点。方法对288例老年住院患者下呼吸道酵母样真菌感染进行回顾性分析。结果社区和医院感染均以白色假丝酵母菌多见,社区感染愈后较好;医院感染多伴有发热和侵入性操作,住院时间较长,与性别、年龄、抗菌药物使用、白细胞等差异无统计学意义;各种真菌对多种抗真菌药物敏感率较高,社区感染的光滑假丝酵母菌对氟康唑和伊曲康唑的敏感性高于医院感染。结论认识老年患者下呼吸道真菌社区与医院感染特点,有助于指导临床。OBJECTIVE To investigate the clinical characteristic of community and nosocomial infections on yeast fungal infection in aged patient. METHODS 288 cases with lower respiratory tract candida infection in hospitalized Geriatric patients were retrospectively analyzed. RESULTS Candida albicans was the most common fungus of community and nosocomial infections. The prognosis of community infections was better. The risk factors of infections were fever, invasive operations and long-term in hospitalized. But there were no differences in sex, age, antibiotic administration, leukocyte count between community and nosocomial infections. The result of drug sensitivity test showed that fungus was sensitive to antifungal agents. The sensitivity of Candida glabrata causing community infections to flueonazole and itraconazole of was higher than that in nosocomial infections. CONCLUSION To study characteristics of community and nosocomial infections on yeast fungal infection in aged patient is beneficial to improve the clinical diagnosis and treatment.

关 键 词：老年患者 下呼吸道 真菌感染 耐药性 医院感染 

分 类 号：R379[医药卫生—病原生物学]