新疆乌鲁木齐市儿童头癣病原菌分析  

Pathogenic fungi of children's tinea capitis in Urumqi,Xinjiang

作　　者：张巧巧[1] 帕丽达.阿布利孜 董潇阳[1] 哈德丽亚[1] 刘旭[1] 周珊[1] 

机构地区：[1]新疆医科大学第一附属医院皮肤科,新疆乌鲁木齐830054

出　　处：《中华医院感染学杂志》2011年第14期3072-3074,共3页Chinese Journal of Nosocomiology

基　　金：国家自然科学基金(30960351);新疆少数民族科技人才特殊培养计划科研项目(200823113);新疆维吾尔自治区人力资源与社会保障厅留学人员科技活动项目择优资助基金;回国人员创业启动基金(2010年度)

摘　　要：目的了解新疆乌鲁木齐市儿童头癣病原菌的分布情况。方法对2003年1月-2010年12月,诊断为头癣的141例患儿,年龄在4月龄～11岁,采集病发及鳞屑真菌镜检、培养,在形态学鉴定的基础上行核糖体DNA(rDNA)ITS区序列测定确切鉴定。结果镜检和培养均为阳性86例占60.99%,镜检阳性、培养阴性46例为32.63%,镜检阴性、培养阳性9例为6.38%,95例培养阳性患儿中男58例、女37例,汉族54例、维吾尔族41例;菌种鉴定结果:犬小孢子菌45株,铁锈色小孢子菌23株,紫色毛癣菌12株,许兰毛癣菌8株,断发毛癣菌5株,疣状毛癣菌2株;不同性别及族别间儿童头癣的发病率差异无统计学意义,不同族别间病原菌分布不同。结论犬小孢子菌为乌鲁木齐市汉族儿童头癣的主要致病菌,铁锈色小孢子菌为维吾尔族儿童头癣主要致病菌,不同民族、不同地区头癣病原菌分布亦有差异。OBJECTIVE To investigate the causative agents of children＇s tinea capitis in Urumuqi city, Xinjiang. METHODS The illness hairs and scales were collected from the tinea capitis children （age from 4 months to 11 year-old） who came to the outpatient of the department of dermatology, the first hospital of Xinjiang Medical University from Jan 2004 to Dec 2010. Collected samples were checked by microscope directly and cultured, identified based on morphology and sequences of ITS regions of rDNA. RESULTS Eighty-six （60.99%） patients showed positive in both of direct microscopic examination and cultivation, 46 patients （32.63 %） positive on direct microscopic examination and negative on cultivation, 9 patients （6.38%） positive on cultivation and negative on direct microscopic exam. Fivety-eight male and 37 female for the 95 culture positive patients, Han patients were 54 and Uyghur were 41. Ninety-five strains were identified base on the morphological characteristics and ITS sequences of rDNA. Forty-five strains of Microsporum canis, 23 strains of Microsporum ferrujenium, 12 strains of Trichophyton violaceum, 8 strains of Trichophyton schoenleinii, 5 strains of Trichophyton tonsurans, and 2 strains of Trichophyton verrucosum were identified. Statistical analysis showed that there were no statistical significant on incidence of children＇s tinea capitis between sexual distinction and race. CONCLUSION Microsporum canis is main causative agent of Han children＇s tinea capitis and Microsporum ferrigenium is main causative agent of Uyghur children＇s tinea capitis in Urumqi city. There are differences of the causative agents of children＇s tinea capitis between different races. There are differences of causative agents of tinea capitis between Urumqi city and Southern Xinjiang where is the tinea capitis high incidence area in Xinjiang.

关 键 词：民族 儿童头癣 病原菌 分析 

分 类 号：R379[医药卫生—病原生物学]