呼出气冷凝液检测技术在机械通气患者中的应用  

Research Progress on Exhaled Breath Condensate in Patients Used Mechanical Ventilation

作　　者：蒋云书[1] 陈建荣[1] 蔡映云[2] 

机构地区：[1]南通大学第二附属医院呼吸科,江苏南通226001 [2]复旦大学附属中山医院呼吸病研究所,上海200032

出　　处：《医学综述》2011年第13期2012-2014,共3页Medical Recapitulate

摘　　要：机械通气是抢救呼吸衰竭患者的重要手段之一,但它可以引起炎性反应、氧化应激,导致通气相关性肺损伤和呼吸机相关性肺炎。呼出气冷凝液(EBC)检测作为一种观察呼吸系统疾病生物学指标的新技术,可动态监测呼吸道炎性反应、氧化应激,用于疾病的诊断和病情评估。随着EBC收集技术和检测方法的改进,EBC检测技术被更多地应用于机械通气患者。现就机械通气患者EBC中相关指标及其临床意义进行综述。Mechanical ventilation was one of very important methods to rescue the patients with respiratory failure,but it can cause ventilator associated lung injury and ventilator associated pneumonia because of inflammation response and oxidative stress.Exhaled breath condensate（EBC）,a new technology for monitoring respiratory disease,was used to detect biochemical markers.It also be used to diagnose and assess the disease by constantly monitoring inflammation response and oxidative stress in airway.With improvement of collecting technique and detecting method,it was more and more applied in mechanically ventilated patients.This article reviewed biochemical markers,which were detected in EBC of mechanically ventilated patients,and their clinical significance.

关 键 词：机械通气 呼出气冷凝液 炎性反应 氧化应激 

分 类 号：R563.8[医药卫生—呼吸系统]