骨科手术中回收血红细胞与患者麻醉前红细胞携氧能力的比较  

Comparison of Oxygen Carrying Capacity of Red Blood Cell in Salvaged Blood of Patients Undergoing Orthopedic Surgery vs Peripheral Blood Before Anesthesia

作　　者：邱颐[1] 丁玉美[1] 崔永武[1] 安敏[1] 

机构地区：[1]内蒙古医学院第二附属医院麻醉科,内蒙古呼和浩特010030

出　　处：《医学临床研究》2011年第6期1080-1082,共3页Journal of Clinical Research

摘　　要：【目的】比较骨科患者术中回收血红细胞与麻醉前红细胞携氧能力的差异。【方法】使用血液回收机对30例骨科手术患者行术中自体血液回收。取血液回收机处理后的回收血和麻醉前患者外周血各30份，检测两组血样的pH、根据公式计算血样的50％氧分压（P50），采用放射免疫法测定红细胞内2，3-二磷酸甘油酸浓度（2，3-DPG）、在血液流变仪上测定红细胞变形指数（RCD）。【结果】回收血样pH值、P50高于麻醉前血样，但无显著性差异（P〉0．05）；2，3-DPG浓度、RCD与麻醉前血样比较差异亦无显著性（P〉0．05）。【结论】骨科患者术中回收血红细胞与麻醉前外周血红细胞具有相同的携氧能力。[ObjectivelTo compare the difference of oxygen carrying capacity of red blood cell between salvaged blood of patients undergoing orthopedic surgery and peripheral blood before anesthesia. [Methods]Thirty patients undergoing orthopedic surgery received autologous blood transfusion by using blood salvage machine during operation. Thirty blood samples in each of salvaged blood processed by blood salvage machine and peripheral blood before anesthesia were drawn. The pH of blood samples in two groups was measured. The formula was used to calculate 50% partial pressure of oxygen （Ps0） in blood samples. The level of 2,3-diphosphoglycerate（2,3-DPG） in erythrocytes was measured by radioimmunoassay and red cell deformability index（RCD） was determined on blood rheology instrument. [Results] The pH and Ps0 in salvaged blood were higher than those in peripheral blood before anesthesia, but there was no significant difference（ P〉0.05）. There was also no significant difference in 2,3-DPG level and RCD between salvaged blood and peripheral blood before anesthesia（ P 〉0.05）.[Conclusion]The oxygen carrying capacity of red blood cell in salvaged blood of patients undergoing orthopedic surgery is the same as that in peripheral blood before anesthesia.

关 键 词：骨科外科手术 红细胞 

分 类 号：R687.3[医药卫生—骨科学]